Torkamani A - Search Results

1

Computational modeling of structurally conserved cancer mutations in the RET and MET kinases: the impact on protein structure, dynamics, and stability.

Dixit A, Torkamani A, Schork NJ, Verkhivker G. Dixit A, et al. Among authors: torkamani a. Biophys J. 2009 Feb;96(3):858-74. doi: 10.1016/j.bpj.2008.10.041. Biophys J. 2009. PMID: 19186126 Free PMC article.

2

Sequence and structure signatures of cancer mutation hotspots in protein kinases.

Dixit A, Yi L, Gowthaman R, Torkamani A, Schork NJ, Verkhivker GM. Dixit A, et al. Among authors: torkamani a. PLoS One. 2009 Oct 16;4(10):e7485. doi: 10.1371/journal.pone.0007485. PLoS One. 2009. PMID: 19834613 Free PMC article.

3

Prediction of cancer driver mutations in protein kinases.

Torkamani A, Schork NJ. Torkamani A, et al. Cancer Res. 2008 Mar 15;68(6):1675-82. doi: 10.1158/0008-5472.CAN-07-5283. Cancer Res. 2008. PMID: 18339846

4

Cancer driver mutations in protein kinase genes.

Torkamani A, Verkhivker G, Schork NJ. Torkamani A, et al. Cancer Lett. 2009 Aug 28;281(2):117-27. doi: 10.1016/j.canlet.2008.11.008. Epub 2008 Dec 10. Cancer Lett. 2009. PMID: 19081671 Free PMC article. Review.

5

Identification of rare cancer driver mutations by network reconstruction.

Torkamani A, Schork NJ. Torkamani A, et al. Genome Res. 2009 Sep;19(9):1570-8. doi: 10.1101/gr.092833.109. Epub 2009 Jul 2. Genome Res. 2009. PMID: 19574499 Free PMC article.

6

Accurate prediction of deleterious protein kinase polymorphisms.

Torkamani A, Schork NJ. Torkamani A, et al. Bioinformatics. 2007 Nov 1;23(21):2918-25. doi: 10.1093/bioinformatics/btm437. Epub 2007 Sep 12. Bioinformatics. 2007. PMID: 17855419

7

Congenital disease SNPs target lineage specific structural elements in protein kinases.

Torkamani A, Kannan N, Taylor SS, Schork NJ. Torkamani A, et al. Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):9011-6. doi: 10.1073/pnas.0802403105. Epub 2008 Jun 25. Proc Natl Acad Sci U S A. 2008. PMID: 18579784 Free PMC article.

8

Kinase mutations in human disease: interpreting genotype-phenotype relationships.

Lahiry P, Torkamani A, Schork NJ, Hegele RA. Lahiry P, et al. Among authors: torkamani a. Nat Rev Genet. 2010 Jan;11(1):60-74. doi: 10.1038/nrg2707. Nat Rev Genet. 2010. PMID: 20019687 Review.

9

Prestige centrality-based functional outlier detection in gene expression analysis.

Torkamani A, Schork NJ. Torkamani A, et al. Bioinformatics. 2009 Sep 1;25(17):2222-8. doi: 10.1093/bioinformatics/btp388. Epub 2009 Jun 23. Bioinformatics. 2009. PMID: 19549629 Free PMC article.

10

Distribution analysis of nonsynonymous polymorphisms within the human kinase gene family.

Torkamani A, Schork NJ. Torkamani A, et al. Genomics. 2007 Jul;90(1):49-58. doi: 10.1016/j.ygeno.2007.03.006. Epub 2007 May 11. Genomics. 2007. PMID: 17498919 Free article.

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