Dalton TP - Search Results

1

Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit.

Lavoie S, Chen Y, Dalton TP, Gysin R, Cuénod M, Steullet P, Do KQ. Lavoie S, et al. Among authors: dalton tp. J Neurochem. 2009 Mar;108(6):1410-22. doi: 10.1111/j.1471-4159.2009.05908.x. Epub 2009 Jan 22. J Neurochem. 2009. PMID: 19183254 Free article.

2

Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response.

Yang Y, Dieter MZ, Chen Y, Shertzer HG, Nebert DW, Dalton TP. Yang Y, et al. Among authors: dalton tp. J Biol Chem. 2002 Dec 20;277(51):49446-52. doi: 10.1074/jbc.M209372200. Epub 2002 Oct 15. J Biol Chem. 2002. PMID: 12384496 Free article.

3

Genetically altered mice to evaluate glutathione homeostasis in health and disease.

Dalton TP, Chen Y, Schneider SN, Nebert DW, Shertzer HG. Dalton TP, et al. Free Radic Biol Med. 2004 Nov 15;37(10):1511-26. doi: 10.1016/j.freeradbiomed.2004.06.040. Free Radic Biol Med. 2004. PMID: 15477003 Review.

4

Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status.

Kann S, Estes C, Reichard JF, Huang MY, Sartor MA, Schwemberger S, Chen Y, Dalton TP, Shertzer HG, Xia Y, Puga A. Kann S, et al. Among authors: dalton tp. Toxicol Sci. 2005 Oct;87(2):365-84. doi: 10.1093/toxsci/kfi253. Epub 2005 Jul 13. Toxicol Sci. 2005. PMID: 16014739

5

Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels.

Chen Y, Shertzer HG, Schneider SN, Nebert DW, Dalton TP. Chen Y, et al. Among authors: dalton tp. J Biol Chem. 2005 Oct 7;280(40):33766-74. doi: 10.1074/jbc.M504604200. Epub 2005 Aug 4. J Biol Chem. 2005. PMID: 16081425 Free article.

6

Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure.

Chen Y, Yang Y, Miller ML, Shen D, Shertzer HG, Stringer KF, Wang B, Schneider SN, Nebert DW, Dalton TP. Chen Y, et al. Among authors: dalton tp. Hepatology. 2007 May;45(5):1118-28. doi: 10.1002/hep.21635. Hepatology. 2007. PMID: 17464988

7

Interaction between the catalytic and modifier subunits of glutamate-cysteine ligase.

Yang Y, Chen Y, Johansson E, Schneider SN, Shertzer HG, Nebert DW, Dalton TP. Yang Y, et al. Among authors: dalton tp. Biochem Pharmacol. 2007 Jul 15;74(2):372-81. doi: 10.1016/j.bcp.2007.02.003. Epub 2007 Feb 12. Biochem Pharmacol. 2007. PMID: 17517378

8

Oxidative and electrophilic stress induces multidrug resistance-associated protein transporters via the nuclear factor-E2-related factor-2 transcriptional pathway.

Maher JM, Dieter MZ, Aleksunes LM, Slitt AL, Guo G, Tanaka Y, Scheffer GL, Chan JY, Manautou JE, Chen Y, Dalton TP, Yamamoto M, Klaassen CD. Maher JM, et al. Among authors: dalton tp. Hepatology. 2007 Nov;46(5):1597-610. doi: 10.1002/hep.21831. Hepatology. 2007. PMID: 17668877

9

Early onset senescence occurs when fibroblasts lack the glutamate-cysteine ligase modifier subunit.

Chen Y, Johansson E, Fan Y, Shertzer HG, Vasiliou V, Nebert DW, Dalton TP. Chen Y, et al. Among authors: dalton tp. Free Radic Biol Med. 2009 Aug 15;47(4):410-8. doi: 10.1016/j.freeradbiomed.2009.05.003. Epub 2009 May 8. Free Radic Biol Med. 2009. PMID: 19427898 Free PMC article.

10

Redox dysregulation affects the ventral but not dorsal hippocampus: impairment of parvalbumin neurons, gamma oscillations, and related behaviors.

Steullet P, Cabungcal JH, Kulak A, Kraftsik R, Chen Y, Dalton TP, Cuenod M, Do KQ. Steullet P, et al. Among authors: dalton tp. J Neurosci. 2010 Feb 17;30(7):2547-58. doi: 10.1523/JNEUROSCI.3857-09.2010. J Neurosci. 2010. PMID: 20164340 Free PMC article.

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