Ryan KC - Search Results

1

Role of conserved tyrosine residues in NiSOD catalysis: a case of convergent evolution.

Herbst RW, Guce A, Bryngelson PA, Higgins KA, Ryan KC, Cabelli DE, Garman SC, Maroney MJ. Herbst RW, et al. Among authors: ryan kc. Biochemistry. 2009 Apr 21;48(15):3354-69. doi: 10.1021/bi802029t. Biochemistry. 2009. PMID: 19183068 Free PMC article.

2

Nickel superoxide dismutase: structural and functional roles of Cys2 and Cys6.

Ryan KC, Johnson OE, Cabelli DE, Brunold TC, Maroney MJ. Ryan KC, et al. J Biol Inorg Chem. 2010 Jun;15(5):795-807. doi: 10.1007/s00775-010-0645-y. Epub 2010 Mar 24. J Biol Inorg Chem. 2010. PMID: 20333421 Free PMC article.

3

Nickel superoxide dismutase: structural and functional roles of His1 and its H-bonding network.

Ryan KC, Guce AI, Johnson OE, Brunold TC, Cabelli DE, Garman SC, Maroney MJ. Ryan KC, et al. Biochemistry. 2015 Feb 3;54(4):1016-27. doi: 10.1021/bi501258u. Epub 2015 Jan 21. Biochemistry. 2015. PMID: 25580509 Free PMC article.

4

The PqrR transcriptional repressor of Pseudomonas aeruginosa transduces redox signals via an iron-containing prosthetic group.

Rungrassamee W, Ryan KC, Maroney MJ, Pomposiello PJ. Rungrassamee W, et al. Among authors: ryan kc. J Bacteriol. 2009 Nov;191(21):6709-21. doi: 10.1128/JB.00932-09. Epub 2009 Aug 28. J Bacteriol. 2009. PMID: 19717597 Free PMC article.

5

Spectroscopic and computational investigation of three Cys-to-Ser mutants of nickel superoxide dismutase: insight into the roles played by the Cys2 and Cys6 active-site residues.

Johnson OE, Ryan KC, Maroney MJ, Brunold TC. Johnson OE, et al. Among authors: ryan kc. J Biol Inorg Chem. 2010 Jun;15(5):777-93. doi: 10.1007/s00775-010-0641-2. Epub 2010 Mar 24. J Biol Inorg Chem. 2010. PMID: 20333422 Free PMC article.

6

The Role of Mixed Amine/Amide Ligation in Nickel Superoxide Dismutase.

Huang HT, Dillon S, Ryan KC, Campecino JO, Watkins OE, Cabelli DE, Brunold TC, Maroney MJ. Huang HT, et al. Among authors: ryan kc. Inorg Chem. 2018 Oct 15;57(20):12521-12535. doi: 10.1021/acs.inorgchem.8b01499. Epub 2018 Oct 3. Inorg Chem. 2018. PMID: 30281299 Free PMC article.

7

Huntingtin plays an essential role in the adult hippocampus.

Barron JC, Dawson LJ, Carew SJ, Grace MC, Senior KA, Ryan KC, Nafar F, Moore CS, Blundell J, Parsons MP. Barron JC, et al. Among authors: ryan kc. Neurobiol Dis. 2025 Jan 22:106810. doi: 10.1016/j.nbd.2025.106810. Online ahead of print. Neurobiol Dis. 2025. PMID: 39855476 Free article.

8

C. elegans Presenilin Mediates Inter-Organelle Contacts and Communication that Is Required for Lysosome Activity.

Ryan KC, Ashkavand Z, Laboy JT, Wang L, Barroso M, Norman KR. Ryan KC, et al. Aging Dis. 2024 Mar 18. doi: 10.14336/AD.2024.0228. Online ahead of print. Aging Dis. 2024. PMID: 38607730

9

Deregulation of Mitochondrial Calcium Handling Due to Presenilin Loss Disrupts Redox Homeostasis and Promotes Neuronal Dysfunction.

Ryan KC, Laboy JT, Norman KR. Ryan KC, et al. Antioxidants (Basel). 2022 Aug 24;11(9):1642. doi: 10.3390/antiox11091642. Antioxidants (Basel). 2022. PMID: 36139715 Free PMC article.

10

Increased mitochondrial calcium uptake and concomitant mitochondrial activity by presenilin loss promotes mTORC1 signaling to drive neurodegeneration.

Ryan KC, Ashkavand Z, Sarasija S, Laboy JT, Samarakoon R, Norman KR. Ryan KC, et al. Aging Cell. 2021 Oct;20(10):e13472. doi: 10.1111/acel.13472. Epub 2021 Sep 9. Aging Cell. 2021. PMID: 34499406 Free PMC article.

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