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Gene therapy for tolerance: high-level expression of donor major histocompatibility complex in the liver overcomes naive and memory alloresponses to skin grafts.
Cunningham EC, Tay SS, Wang C, Rtshiladze M, Wang ZZ, McGuffog C, Cubitt J, McCaughan GW, Alexander IE, Bertolino P, Sharland AF, Bowen DG, Bishop GA. Cunningham EC, et al. Among authors: tay ss. Transplantation. 2013 Jan 15;95(1):70-7. doi: 10.1097/TP.0b013e318278d39a. Transplantation. 2013. PMID: 23263501
Adeno-associated virus serotypes for gene therapeutics.
Lisowski L, Tay SS, Alexander IE. Lisowski L, et al. Among authors: tay ss. Curr Opin Pharmacol. 2015 Oct;24:59-67. doi: 10.1016/j.coph.2015.07.006. Epub 2015 Aug 25. Curr Opin Pharmacol. 2015. PMID: 26291407 Review.
Direct recognition of hepatocyte-expressed MHC class I alloantigens is required for tolerance induction.
Paul-Heng M, Leong M, Cunningham E, Bunker DLJ, Bremner K, Wang Z, Wang C, Tay SS, McGuffog C, Logan GJ, Alexander IE, Hu M, Alexander SI, Sparwasser TD, Bertolino P, Bowen DG, Bishop GA, Sharland A. Paul-Heng M, et al. Among authors: tay ss. JCI Insight. 2018 Aug 9;3(15):e97500. doi: 10.1172/jci.insight.97500. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089715 Free PMC article.
Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells.
Tay SS, Wong YC, Roediger B, Sierro F, Lu B, McDonald DM, McGuffog CM, Meyer NJ, Alexander IE, Parish IA, Heath WR, Weninger W, Bishop GA, Gamble JR, McCaughan GW, Bertolino P, Bowen DG. Tay SS, et al. J Immunol. 2014 Sep 1;193(5):2087-95. doi: 10.4049/jimmunol.1400037. Epub 2014 Jul 28. J Immunol. 2014. PMID: 25070847
170 results