Leban J - Search Results

1

The peptide-semicarbazone S-2209, a representative of a new class of proteasome inhibitors, induces apoptosis and cell growth arrest in multiple myeloma cells.

Baumann P, Müller K, Mandl-Weber S, Leban J, Doblhofer R, Ammendola A, Baumgartner R, Oduncu F, Schmidmaier R. Baumann P, et al. Among authors: leban j. Br J Haematol. 2009 Mar;144(6):875-86. doi: 10.1111/j.1365-2141.2008.07570.x. Epub 2009 Jan 16. Br J Haematol. 2009. PMID: 19170678 Free article.

2

The novel, proteasome-independent NF-kappaB inhibitor V1810 induces apoptosis and cell cycle arrest in multiple myeloma and overcomes NF-kappaB-mediated drug resistance.

Meinel FG, Mandl-Weber S, Baumann P, Leban J, Schmidmaier R. Meinel FG, et al. Among authors: leban j. Mol Cancer Ther. 2010 Feb;9(2):300-10. doi: 10.1158/1535-7163.MCT-09-0645. Epub 2010 Feb 2. Mol Cancer Ther. 2010. PMID: 20124446

3

Proteasome inhibition by peptide-semicarbazones.

Leban J, Blisse M, Krauss B, Rath S, Baumgartner R, Seifert MH. Leban J, et al. Bioorg Med Chem. 2008 Apr 15;16(8):4579-88. doi: 10.1016/j.bmc.2008.02.042. Epub 2008 Feb 15. Bioorg Med Chem. 2008. PMID: 18313310

4

4SC-101, a novel small molecule dihydroorotate dehydrogenase inhibitor, suppresses systemic lupus erythematosus in MRL-(Fas)lpr mice.

Kulkarni OP, Sayyed SG, Kantner C, Ryu M, Schnurr M, Sárdy M, Leban J, Jankowsky R, Ammendola A, Doblhofer R, Anders HJ. Kulkarni OP, et al. Among authors: leban j. Am J Pathol. 2010 Jun;176(6):2840-7. doi: 10.2353/ajpath.2010.091227. Epub 2010 Apr 22. Am J Pathol. 2010. PMID: 20413687 Free PMC article.

5

Immunosuppression with 4SC-101, a novel inhibitor of dihydroorotate dehydrogenase, in a rat model of renal transplantation.

Rusai K, Schmaderer C, Baumann M, Chmielewski S, Prókai A, Kis E, Szabó AJ, Leban J, Doblhofer R, Ammendola A, Lutz J, Heemann U. Rusai K, et al. Among authors: leban j. Transplantation. 2012 Jun 15;93(11):1101-7. doi: 10.1097/TP.0b013e31824fd861. Transplantation. 2012. PMID: 22609757

6

Discovery of a novel series of DHODH inhibitors by a docking procedure and QSAR refinement.

Leban J, Saeb W, Garcia G, Baumgartner R, Kramer B. Leban J, et al. Bioorg Med Chem Lett. 2004 Jan 5;14(1):55-8. doi: 10.1016/j.bmcl.2003.10.021. Bioorg Med Chem Lett. 2004. PMID: 14684297

7

SAR, species specificity, and cellular activity of cyclopentene dicarboxylic acid amides as DHODH inhibitors.

Leban J, Kralik M, Mies J, Gassen M, Tentschert K, Baumgartner R. Leban J, et al. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4854-7. doi: 10.1016/j.bmcl.2005.07.053. Bioorg Med Chem Lett. 2005. PMID: 16143532

8

Dual binding mode of a novel series of DHODH inhibitors.

Baumgartner R, Walloschek M, Kralik M, Gotschlich A, Tasler S, Mies J, Leban J. Baumgartner R, et al. Among authors: leban j. J Med Chem. 2006 Feb 23;49(4):1239-47. doi: 10.1021/jm0506975. J Med Chem. 2006. PMID: 16480261

9

Biphenyl-4-ylcarbamoyl thiophene carboxylic acids as potent DHODH inhibitors.

Leban J, Kralik M, Mies J, Baumgartner R, Gassen M, Tasler S. Leban J, et al. Bioorg Med Chem Lett. 2006 Jan 15;16(2):267-70. doi: 10.1016/j.bmcl.2005.10.011. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246558

10

A novel class of potent NF-kappaB signaling inhibitors.

Leban J, Baierl M, Mies J, Trentinaglia V, Rath S, Kronthaler K, Wolf K, Gotschlich A, Seifert MH. Leban J, et al. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5858-62. doi: 10.1016/j.bmcl.2007.08.022. Epub 2007 Aug 15. Bioorg Med Chem Lett. 2007. PMID: 17869512

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