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Pravastatin reduces myocardial infarct size via increasing protein kinase C-dependent nitric oxide, decreasing oxyradicals and opening the mitochondrial adenosine triphosphate-sensitive potassium channels in rabbits.
Bao N, Minatoguchi S, Kobayashi H, Yasuda S, Kawamura I, Iwasa M, Yamaki T, Sumi S, Misao Y, Arai M, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H. Bao N, et al. Among authors: kawamura i. Circ J. 2007 Oct;71(10):1622-8. doi: 10.1253/circj.71.1622. Circ J. 2007. PMID: 17895562 Free article.
Can negative cardiac effect of proton pump inhibitor and high-dose H2-blocker have clinical influence on patients with stable angina?
Tanaka S, Nishigaki K, Ojio S, Okubo M, Yasuda S, Ishihara Y, Kubota T, Takasugi N, Kawamura I, Yamaki T, Ushikoshi H, Aoyama T, Kawasaki M, Takemura G, Minatoguchi S. Tanaka S, et al. Among authors: kawamura i. J Cardiol. 2008 Aug;52(1):39-48. doi: 10.1016/j.jjcc.2008.05.004. Epub 2008 Jun 30. J Cardiol. 2008. PMID: 18639776 Free article.
Antidiabetic drug pioglitazone protects the heart via activation of PPAR-gamma receptors, PI3-kinase, Akt, and eNOS pathway in a rabbit model of myocardial infarction.
Yasuda S, Kobayashi H, Iwasa M, Kawamura I, Sumi S, Narentuoya B, Yamaki T, Ushikoshi H, Nishigaki K, Nagashima K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Yasuda S, et al. Among authors: kawamura i. Am J Physiol Heart Circ Physiol. 2009 May;296(5):H1558-65. doi: 10.1152/ajpheart.00712.2008. Epub 2009 Mar 13. Am J Physiol Heart Circ Physiol. 2009. PMID: 19286954 Free article.
Acarbose reduces myocardial infarct size by preventing postprandial hyperglycemia and hydroxyl radical production and opening mitochondrial KATP channels in rabbits.
Minatoguchi S, Zhang Z, Bao N, Kobayashi H, Yasuda S, Iwasa M, Sumi S, Kawamura I, Yamada Y, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H. Minatoguchi S, et al. Among authors: kawamura i. J Cardiovasc Pharmacol. 2009 Jul;54(1):25-30. doi: 10.1097/FJC.0b013e3181a98b53. J Cardiovasc Pharmacol. 2009. PMID: 19487955
Postinfarct treatment with oxytocin improves cardiac function and remodeling via activating cell-survival signals and angiogenesis.
Kobayashi H, Yasuda S, Bao N, Iwasa M, Kawamura I, Yamada Y, Yamaki T, Sumi S, Ushikoshi H, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Kobayashi H, et al. Among authors: kawamura i. J Cardiovasc Pharmacol. 2009 Dec;54(6):510-9. doi: 10.1097/FJC.0b013e3181bfac02. J Cardiovasc Pharmacol. 2009. PMID: 19755919
Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits.
Iwasa M, Kobayashi H, Yasuda S, Kawamura I, Sumi S, Yamada Y, Shiraki T, Yamaki T, Ushikoshi H, Aoyama T, Nishigaki K, Takemura G, Fujiwara T, Fujiwara H, Minatoguchi S. Iwasa M, et al. Among authors: kawamura i. J Cardiovasc Pharmacol. 2010 Jun;55(6):625-34. doi: 10.1097/FJC.0b013e3181dcd240. J Cardiovasc Pharmacol. 2010. PMID: 20351564
Both stimulation of GLP-1 receptors and inhibition of glycogenolysis additively contribute to a protective effect of oral miglitol against ischaemia-reperfusion injury in rabbits.
Iwasa M, Yamada Y, Kobayashi H, Yasuda S, Kawamura I, Sumi S, Shiraki T, Yamaki T, Ushikoshi H, Hattori A, Aoyama T, Nishigaki K, Takemura G, Fujiwara H, Minatoguchi S. Iwasa M, et al. Among authors: kawamura i. Br J Pharmacol. 2011 Sep;164(1):119-31. doi: 10.1111/j.1476-5381.2011.01357.x. Br J Pharmacol. 2011. PMID: 21426318 Free PMC article.
481 results