Beer D - Search Results

1

Discovery of a non-peptidic inhibitor of west nile virus NS3 protease by high-throughput docking.

Ekonomiuk D, Su XC, Ozawa K, Bodenreider C, Lim SP, Yin Z, Keller TH, Beer D, Patel V, Otting G, Caflisch A, Huang D. Ekonomiuk D, et al. Among authors: beer d. PLoS Negl Trop Dis. 2009;3(1):e356. doi: 10.1371/journal.pntd.0000356. Epub 2009 Jan 13. PLoS Negl Trop Dis. 2009. PMID: 19159012 Free PMC article.

2

Peptide inhibitors of Dengue virus NS3 protease. Part 1: Warhead.

Yin Z, Patel SJ, Wang WL, Wang G, Chan WL, Rao KR, Alam J, Jeyaraj DA, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: beer d. Bioorg Med Chem Lett. 2006 Jan 1;16(1):36-9. doi: 10.1016/j.bmcl.2005.09.062. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246553

3

Peptide inhibitors of West Nile NS3 protease: SAR study of tetrapeptide aldehyde inhibitors.

Knox JE, Ma NL, Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Lim SP, Vasudevan SG, Keller TH. Knox JE, et al. Among authors: beer d. J Med Chem. 2006 Nov 2;49(22):6585-90. doi: 10.1021/jm0607606. J Med Chem. 2006. PMID: 17064076

4

Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitors.

Yin Z, Patel SJ, Wang WL, Chan WL, Ranga Rao KR, Wang G, Ngew X, Patel V, Beer D, Knox JE, Ma NL, Ehrhardt C, Lim SP, Vasudevan SG, Keller TH. Yin Z, et al. Among authors: beer d. Bioorg Med Chem Lett. 2006 Jan 1;16(1):40-3. doi: 10.1016/j.bmcl.2005.09.049. Epub 2005 Oct 21. Bioorg Med Chem Lett. 2006. PMID: 16246563

5

A fluorescence quenching assay to discriminate between specific and nonspecific inhibitors of dengue virus protease.

Bodenreider C, Beer D, Keller TH, Sonntag S, Wen D, Yap L, Yau YH, Shochat SG, Huang D, Zhou T, Caflisch A, Su XC, Ozawa K, Otting G, Vasudevan SG, Lescar J, Lim SP. Bodenreider C, et al. Among authors: beer d. Anal Biochem. 2009 Dec 15;395(2):195-204. doi: 10.1016/j.ab.2009.08.013. Epub 2009 Aug 13. Anal Biochem. 2009. PMID: 19682971

6

Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening.

Niyomrattanakit P, Wan KF, Chung KY, Abas SN, Seh CC, Dong H, Lim CC, Chao AT, Lee CB, Nilar S, Lescar J, Shi PY, Beer D, Lim SP. Niyomrattanakit P, et al. Among authors: beer d. Antiviral Res. 2015 Jul;119:36-46. doi: 10.1016/j.antiviral.2015.04.007. Epub 2015 Apr 18. Antiviral Res. 2015. PMID: 25896272

7

Efficient elimination of nonstoichiometric enzyme inhibitors from HTS hit lists.

Habig M, Blechschmidt A, Dressler S, Hess B, Patel V, Billich A, Ostermeier C, Beer D, Klumpp M. Habig M, et al. Among authors: beer d. J Biomol Screen. 2009 Jul;14(6):679-89. doi: 10.1177/1087057109336586. Epub 2009 May 21. J Biomol Screen. 2009. PMID: 19470716

8

Ten years of dengue drug discovery: progress and prospects.

Lim SP, Wang QY, Noble CG, Chen YL, Dong H, Zou B, Yokokawa F, Nilar S, Smith P, Beer D, Lescar J, Shi PY. Lim SP, et al. Among authors: beer d. Antiviral Res. 2013 Nov;100(2):500-19. doi: 10.1016/j.antiviral.2013.09.013. Epub 2013 Sep 27. Antiviral Res. 2013. PMID: 24076358 Review.

9

Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries.

Li J, Lim SP, Beer D, Patel V, Wen D, Tumanut C, Tully DC, Williams JA, Jiricek J, Priestle JP, Harris JL, Vasudevan SG. Li J, et al. Among authors: beer d. J Biol Chem. 2005 Aug 5;280(31):28766-74. doi: 10.1074/jbc.M500588200. Epub 2005 Jun 1. J Biol Chem. 2005. PMID: 15932883 Free article.

10

Identifying initiation and elongation inhibitors of dengue virus RNA polymerase in a high-throughput lead-finding campaign.

Smith TM, Lim SP, Yue K, Busby SA, Arora R, Seh CC, Wright SK, Nutiu R, Niyomrattanakit P, Wan KF, Beer D, Shi PY, Benson TE. Smith TM, et al. Among authors: beer d. J Biomol Screen. 2015 Jan;20(1):153-63. doi: 10.1177/1087057114551141. Epub 2014 Sep 24. J Biomol Screen. 2015. PMID: 25252731

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