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IGFBP3 colocalizes with and regulates hypocretin (orexin).
Honda M, Eriksson KS, Zhang S, Tanaka S, Lin L, Salehi A, Hesla PE, Maehlen J, Gaus SE, Yanagisawa M, Sakurai T, Taheri S, Tsuchiya K, Honda Y, Mignot E. Honda M, et al. Among authors: sakurai t. PLoS One. 2009;4(1):e4254. doi: 10.1371/journal.pone.0004254. Epub 2009 Jan 22. PLoS One. 2009. PMID: 19158946 Free PMC article.
Hypothalamic orexin neurons regulate arousal according to energy balance in mice.
Yamanaka A, Beuckmann CT, Willie JT, Hara J, Tsujino N, Mieda M, Tominaga M, Yagami Ki, Sugiyama F, Goto K, Yanagisawa M, Sakurai T. Yamanaka A, et al. Among authors: sakurai t. Neuron. 2003 Jun 5;38(5):701-13. doi: 10.1016/s0896-6273(03)00331-3. Neuron. 2003. PMID: 12797956 Free article.
Orexins (hypocretins) directly interact with neuropeptide Y, POMC and glucose-responsive neurons to regulate Ca 2+ signaling in a reciprocal manner to leptin: orexigenic neuronal pathways in the mediobasal hypothalamus.
Muroya S, Funahashi H, Yamanaka A, Kohno D, Uramura K, Nambu T, Shibahara M, Kuramochi M, Takigawa M, Yanagisawa M, Sakurai T, Shioda S, Yada T. Muroya S, et al. Among authors: sakurai t. Eur J Neurosci. 2004 Mar;19(6):1524-34. doi: 10.1111/j.1460-9568.2004.03255.x. Eur J Neurosci. 2004. PMID: 15066149
Behavioral state instability in orexin knock-out mice.
Mochizuki T, Crocker A, McCormack S, Yanagisawa M, Sakurai T, Scammell TE. Mochizuki T, et al. Among authors: sakurai t. J Neurosci. 2004 Jul 14;24(28):6291-300. doi: 10.1523/JNEUROSCI.0586-04.2004. J Neurosci. 2004. PMID: 15254084 Free PMC article.
Variants of the orexin2/hcrt2 receptor gene identified in patients with excessive daytime sleepiness and patients with Tourette's syndrome comorbidity.
Thompson MD, Comings DE, Abu-Ghazalah R, Jereseh Y, Lin L, Wade J, Sakurai T, Tokita S, Yoshida T, Tanaka H, Yanagisawa M, Burnham WM, Moldofsky H. Thompson MD, et al. Among authors: sakurai t. Am J Med Genet B Neuropsychiatr Genet. 2004 Aug 15;129B(1):69-75. doi: 10.1002/ajmg.b.30047. Am J Med Genet B Neuropsychiatr Genet. 2004. PMID: 15274044
3,549 results