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916 results

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Page 1
Ectopic expression of the homeobox gene Cdx2 is the transforming event in a mouse model of t(12;13)(p13;q12) acute myeloid leukemia.
Rawat VP, Cusan M, Deshpande A, Hiddemann W, Quintanilla-Martinez L, Humphries RK, Bohlander SK, Feuring-Buske M, Buske C. Rawat VP, et al. Among authors: hiddemann w. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):817-22. doi: 10.1073/pnas.0305555101. Epub 2004 Jan 12. Proc Natl Acad Sci U S A. 2004. PMID: 14718672 Free PMC article.
Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia.
Rawat VP, Thoene S, Naidu VM, Arseni N, Heilmeier B, Metzeler K, Petropoulos K, Deshpande A, Quintanilla-Martinez L, Bohlander SK, Spiekermann K, Hiddemann W, Feuring-Buske M, Buske C. Rawat VP, et al. Among authors: hiddemann w. Blood. 2008 Jan 1;111(1):309-19. doi: 10.1182/blood-2007-04-085407. Epub 2007 Sep 12. Blood. 2008. PMID: 17855634 Free article.
The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia.
Rawat VP, Arseni N, Ahmed F, Mulaw MA, Thoene S, Heilmeier B, Sadlon T, D'Andrea RJ, Hiddemann W, Bohlander SK, Buske C, Feuring-Buske M. Rawat VP, et al. Among authors: hiddemann w. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16946-51. doi: 10.1073/pnas.1001878107. Epub 2010 Sep 10. Proc Natl Acad Sci U S A. 2010. PMID: 20833819 Free PMC article.
High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature.
Herold T, Mulaw MA, Jurinovic V, Seiler T, Metzeler KH, Dufour A, Schneider S, Kakadia PM, Spiekermann K, Mansmann U, Hiddemann W, Buske C, Dreyling M, Bohlander SK. Herold T, et al. Among authors: hiddemann w. Leuk Lymphoma. 2013 Aug;54(8):1652-7. doi: 10.3109/10428194.2012.753445. Epub 2012 Dec 27. Leuk Lymphoma. 2013. PMID: 23189934
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
Rothenberg-Thurley M, Amler S, Goerlich D, Köhnke T, Konstandin NP, Schneider S, Sauerland MC, Herold T, Hubmann M, Ksienzyk B, Zellmeier E, Bohlander SK, Subklewe M, Faldum A, Hiddemann W, Braess J, Spiekermann K, Metzeler KH. Rothenberg-Thurley M, et al. Among authors: hiddemann w. Leukemia. 2018 Jul;32(7):1598-1608. doi: 10.1038/s41375-018-0034-z. Epub 2018 Feb 23. Leukemia. 2018. PMID: 29472724 Free PMC article.
The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia.
Angenendt L, Bormann E, Pabst C, Alla V, Görlich D, Braun L, Dohlich K, Schwöppe C, Bohlander SK, Arteaga MF, Wethmar K, Hartmann W, Angenendt A, Kessler T, Mesters RM, Stelljes M, Rothenberg-Thurley M, Spiekermann K, Hébert J, Sauvageau G, Valk PJM, Löwenberg B, Serve H, Müller-Tidow C, Lenz G, Wörmann BJ, Sauerland MC, Hiddemann W, Berdel WE, Krug U, Metzeler KH, Mikesch JH, Herold T, Schliemann C. Angenendt L, et al. Among authors: hiddemann w. Leukemia. 2019 Dec;33(12):2830-2841. doi: 10.1038/s41375-019-0505-x. Epub 2019 Jun 10. Leukemia. 2019. PMID: 31182782
The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice.
Deshpande AJ, Rouhi A, Lin Y, Stadler C, Greif PA, Arseni N, Opatz S, Quintanilla-Fend L, Holzmann K, Hiddemann W, Döhner K, Döhner H, Xu G, Armstrong SA, Bohlander SK, Buske C. Deshpande AJ, et al. Among authors: hiddemann w. Leukemia. 2011 Nov;25(11):1718-27. doi: 10.1038/leu.2011.153. Epub 2011 Jun 17. Leukemia. 2011. PMID: 21681188
The leukemogenicity of Hoxa9 depends on alternative splicing.
Stadler CR, Vegi N, Mulaw MA, Edmaier KE, Rawat VP, Dolnik A, Bullinger L, Heilmeier B, Quintanilla-Fend L, Spiekermann K, Hiddemann W, Döhner K, Döhner H, Feuring-Buske M, Buske C. Stadler CR, et al. Among authors: hiddemann w. Leukemia. 2014 Sep;28(9):1838-43. doi: 10.1038/leu.2014.74. Epub 2014 Feb 18. Leukemia. 2014. PMID: 24535405
916 results