Conrad D - Search Results

1

ADAMs 10 and 17 represent differentially regulated components of a general shedding machinery for membrane proteins such as transforming growth factor alpha, L-selectin, and tumor necrosis factor alpha.

Le Gall SM, Bobé P, Reiss K, Horiuchi K, Niu XD, Lundell D, Gibb DR, Conrad D, Saftig P, Blobel CP. Le Gall SM, et al. Among authors: conrad d. Mol Biol Cell. 2009 Mar;20(6):1785-94. doi: 10.1091/mbc.e08-11-1135. Epub 2009 Jan 21. Mol Biol Cell. 2009. PMID: 19158376 Free PMC article.

2

ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23.

Weskamp G, Ford JW, Sturgill J, Martin S, Docherty AJ, Swendeman S, Broadway N, Hartmann D, Saftig P, Umland S, Sehara-Fujisawa A, Black RA, Ludwig A, Becherer JD, Conrad DH, Blobel CP. Weskamp G, et al. Among authors: conrad dh. Nat Immunol. 2006 Dec;7(12):1293-8. doi: 10.1038/ni1399. Epub 2006 Oct 29. Nat Immunol. 2006. PMID: 17072319

3

The emergence of ADAM10 as a regulator of lymphocyte development and autoimmunity.

Gibb DR, Saleem SJ, Chaimowitz NS, Mathews J, Conrad DH. Gibb DR, et al. Mol Immunol. 2011 Jun;48(11):1319-27. doi: 10.1016/j.molimm.2010.12.005. Epub 2011 Jan 13. Mol Immunol. 2011. PMID: 21236490 Free PMC article. Review.

4

CD23 Sheddase A disintegrin and metalloproteinase 10 (ADAM10) is also required for CD23 sorting into B cell-derived exosomes.

Mathews JA, Gibb DR, Chen BH, Scherle P, Conrad DH. Mathews JA, et al. J Biol Chem. 2010 Nov 26;285(48):37531-41. doi: 10.1074/jbc.M110.141556. Epub 2010 Sep 28. J Biol Chem. 2010. PMID: 20876574 Free PMC article.

5

ADAM10 overexpression shifts lympho- and myelopoiesis by dysregulating site 2/site 3 cleavage products of Notch.

Gibb DR, Saleem SJ, Kang DJ, Subler MA, Conrad DH. Gibb DR, et al. J Immunol. 2011 Apr 1;186(7):4244-52. doi: 10.4049/jimmunol.1003318. Epub 2011 Mar 2. J Immunol. 2011. PMID: 21368228 Free PMC article.

6

A disintegrin and metalloproteinase 10 regulates antibody production and maintenance of lymphoid architecture.

Chaimowitz NS, Martin RK, Cichy J, Gibb DR, Patil P, Kang DJ, Farnsworth J, Butcher EC, McCright B, Conrad DH. Chaimowitz NS, et al. J Immunol. 2011 Nov 15;187(10):5114-22. doi: 10.4049/jimmunol.1102172. Epub 2011 Oct 12. J Immunol. 2011. PMID: 21998451 Free PMC article.

7

ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo.

Gibb DR, El Shikh M, Kang DJ, Rowe WJ, El Sayed R, Cichy J, Yagita H, Tew JG, Dempsey PJ, Crawford HC, Conrad DH. Gibb DR, et al. J Exp Med. 2010 Mar 15;207(3):623-35. doi: 10.1084/jem.20091990. Epub 2010 Feb 15. J Exp Med. 2010. PMID: 20156974 Free PMC article.

8

A potential new target for asthma therapy: a disintegrin and metalloprotease 10 (ADAM10) involvement in murine experimental asthma.

Mathews JA, Ford J, Norton S, Kang D, Dellinger A, Gibb DR, Ford AQ, Massay H, Kepley CL, Scherle P, Keegan AD, Conrad DH. Mathews JA, et al. Among authors: conrad dh. Allergy. 2011 Sep;66(9):1193-200. doi: 10.1111/j.1398-9995.2011.02614.x. Epub 2011 May 10. Allergy. 2011. PMID: 21557750 Free PMC article.

9

CD23: an overlooked regulator of allergic disease.

Conrad DH, Ford JW, Sturgill JL, Gibb DR. Conrad DH, et al. Curr Allergy Asthma Rep. 2007 Sep;7(5):331-7. doi: 10.1007/s11882-007-0050-y. Curr Allergy Asthma Rep. 2007. PMID: 17697638

10

Regulation of the IgE response.

Conrad DH, Gibb DR, Sturgill J. Conrad DH, et al. F1000 Biol Rep. 2010 Feb 24;2:14. doi: 10.3410/B2-14. F1000 Biol Rep. 2010. PMID: 20948818 Free PMC article.

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