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Restored degradation of the Alzheimer's amyloid-beta peptide by targeting amyloid formation.
Crouch PJ, Tew DJ, Du T, Nguyen DN, Caragounis A, Filiz G, Blake RE, Trounce IA, Soon CP, Laughton K, Perez KA, Li QX, Cherny RA, Masters CL, Barnham KJ, White AR. Crouch PJ, et al. Among authors: tew dj. J Neurochem. 2009 Mar;108(5):1198-207. doi: 10.1111/j.1471-4159.2009.05870.x. Epub 2009 Jan 7. J Neurochem. 2009. PMID: 19141082 Free article.
Platinum-based inhibitors of amyloid-beta as therapeutic agents for Alzheimer's disease.
Barnham KJ, Kenche VB, Ciccotosto GD, Smith DP, Tew DJ, Liu X, Perez K, Cranston GA, Johanssen TJ, Volitakis I, Bush AI, Masters CL, White AR, Smith JP, Cherny RA, Cappai R. Barnham KJ, et al. Among authors: tew dj. Proc Natl Acad Sci U S A. 2008 May 13;105(19):6813-8. doi: 10.1073/pnas.0800712105. Epub 2008 May 7. Proc Natl Acad Sci U S A. 2008. PMID: 18463291 Free PMC article.
Neurotoxic, redox-competent Alzheimer's beta-amyloid is released from lipid membrane by methionine oxidation.
Barnham KJ, Ciccotosto GD, Tickler AK, Ali FE, Smith DG, Williamson NA, Lam YH, Carrington D, Tew D, Kocak G, Volitakis I, Separovic F, Barrow CJ, Wade JD, Masters CL, Cherny RA, Curtain CC, Bush AI, Cappai R. Barnham KJ, et al. J Biol Chem. 2003 Oct 31;278(44):42959-65. doi: 10.1074/jbc.M305494200. Epub 2003 Aug 18. J Biol Chem. 2003. PMID: 12925530 Free article.
31 results