Finck BN - Search Results

1

Lipin 2 is a liver-enriched phosphatidate phosphohydrolase enzyme that is dynamically regulated by fasting and obesity in mice.

Gropler MC, Harris TE, Hall AM, Wolins NE, Gross RW, Han X, Chen Z, Finck BN. Gropler MC, et al. Among authors: finck bn. J Biol Chem. 2009 Mar 13;284(11):6763-72. doi: 10.1074/jbc.M807882200. Epub 2009 Jan 10. J Biol Chem. 2009. PMID: 19136718 Free PMC article.

2

The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus.

Finck BN, Lehman JJ, Leone TC, Welch MJ, Bennett MJ, Kovacs A, Han X, Gross RW, Kozak R, Lopaschuk GD, Kelly DP. Finck BN, et al. J Clin Invest. 2002 Jan;109(1):121-30. doi: 10.1172/JCI14080. J Clin Invest. 2002. PMID: 11781357 Free PMC article.

3

A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

Finck BN, Han X, Courtois M, Aimond F, Nerbonne JM, Kovacs A, Gross RW, Kelly DP. Finck BN, et al. Proc Natl Acad Sci U S A. 2003 Feb 4;100(3):1226-31. doi: 10.1073/pnas.0336724100. Epub 2003 Jan 27. Proc Natl Acad Sci U S A. 2003. PMID: 12552126 Free PMC article.

4

G-protein signaling participates in the development of diabetic cardiomyopathy.

Harris IS, Treskov I, Rowley MW, Heximer S, Kaltenbronn K, Finck BN, Gross RW, Kelly DP, Blumer KJ, Muslin AJ. Harris IS, et al. Among authors: finck bn. Diabetes. 2004 Dec;53(12):3082-90. doi: 10.2337/diabetes.53.12.3082. Diabetes. 2004. PMID: 15561937

5

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP. Leone TC, et al. Among authors: finck bn. PLoS Biol. 2005 Apr;3(4):e101. doi: 10.1371/journal.pbio.0030101. Epub 2005 Mar 15. PLoS Biol. 2005. PMID: 15760270 Free PMC article.

6

Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.

Burgess SC, Leone TC, Wende AR, Croce MA, Chen Z, Sherry AD, Malloy CR, Finck BN. Burgess SC, et al. Among authors: finck bn. J Biol Chem. 2006 Jul 14;281(28):19000-8. doi: 10.1074/jbc.M600050200. Epub 2006 May 2. J Biol Chem. 2006. PMID: 16670093 Free PMC article.

7

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway.

Finck BN, Gropler MC, Chen Z, Leone TC, Croce MA, Harris TE, Lawrence JC Jr, Kelly DP. Finck BN, et al. Cell Metab. 2006 Sep;4(3):199-210. doi: 10.1016/j.cmet.2006.08.005. Cell Metab. 2006. PMID: 16950137 Free article.

8

OXPAT/PAT-1 is a PPAR-induced lipid droplet protein that promotes fatty acid utilization.

Wolins NE, Quaynor BK, Skinner JR, Tzekov A, Croce MA, Gropler MC, Varma V, Yao-Borengasser A, Rasouli N, Kern PA, Finck BN, Bickel PE. Wolins NE, et al. Among authors: finck bn. Diabetes. 2006 Dec;55(12):3418-28. doi: 10.2337/db06-0399. Diabetes. 2006. PMID: 17130488

9

CD36 deficiency rescues lipotoxic cardiomyopathy.

Yang J, Sambandam N, Han X, Gross RW, Courtois M, Kovacs A, Febbraio M, Finck BN, Kelly DP. Yang J, et al. Among authors: finck bn. Circ Res. 2007 Apr 27;100(8):1208-17. doi: 10.1161/01.RES.0000264104.25265.b6. Epub 2007 Mar 15. Circ Res. 2007. PMID: 17363697

10

Hepatic lipin 1beta expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss.

Croce MA, Eagon JC, LaRiviere LL, Korenblat KM, Klein S, Finck BN. Croce MA, et al. Among authors: finck bn. Diabetes. 2007 Sep;56(9):2395-9. doi: 10.2337/db07-0480. Epub 2007 Jun 11. Diabetes. 2007. PMID: 17563064

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