Li H - Search Results

1

3D-QSAR studies of HDACs inhibitors using pharmacophore-based alignment.

Chen Y, Li H, Tang W, Zhu C, Jiang Y, Zou J, Yu Q, You Q. Chen Y, et al. Among authors: li h. Eur J Med Chem. 2009 Jul;44(7):2868-76. doi: 10.1016/j.ejmech.2008.12.008. Epub 2008 Dec 16. Eur J Med Chem. 2009. PMID: 19136179

2

Pharmacophore identification of Raf-1 kinase inhibitors.

Zhu T, Jiao Y, Chen YD, Wang X, Li HF, Zhang LY, Lu T. Zhu T, et al. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2346-50. doi: 10.1016/j.bmcl.2008.02.068. Epub 2008 Mar 4. Bioorg Med Chem Lett. 2008. PMID: 18346893

3

Virtual screening for Raf-1 kinase inhibitors based on pharmacophore model of substituted ureas.

Li HF, Lu T, Zhu T, Jiang YJ, Rao SS, Hu LY, Xin BT, Chen YD. Li HF, et al. Eur J Med Chem. 2009 Mar;44(3):1240-9. doi: 10.1016/j.ejmech.2008.09.016. Epub 2008 Sep 23. Eur J Med Chem. 2009. PMID: 18947905

4

Discovery, optimization and biological evaluation for novel c-Met kinase inhibitors.

Yuan H, Liu Q, Zhang L, Hu S, Chen T, Li H, Chen Y, Xu Y, Lu T. Yuan H, et al. Among authors: li h. Eur J Med Chem. 2018 Jan 1;143:491-502. doi: 10.1016/j.ejmech.2017.11.073. Epub 2017 Dec 2. Eur J Med Chem. 2018. PMID: 29202410

5

Structure-based and shape-complemented pharmacophore modeling for the discovery of novel checkpoint kinase 1 inhibitors.

Chen XM, Lu T, Lu S, Li HF, Yuan HL, Ran T, Liu HC, Chen YD. Chen XM, et al. J Mol Model. 2010 Jul;16(7):1195-204. doi: 10.1007/s00894-009-0630-y. Epub 2009 Dec 18. J Mol Model. 2010. PMID: 20020310

6

Investigation on the isoform selectivity of histone deacetylase inhibitors using chemical feature based pharmacophore and docking approaches.

Zhu Y, Li HF, Lu S, Zheng YX, Wu Z, Tang WF, Zhou X, Lu T. Zhu Y, et al. Eur J Med Chem. 2010 May;45(5):1777-91. doi: 10.1016/j.ejmech.2010.01.010. Epub 2010 Jan 28. Eur J Med Chem. 2010. PMID: 20153566

7

Recent advances in the research and development of B-Raf inhibitors.

Li HF, Chen Y, Rao SS, Chen XM, Liu HC, Qin JH, Tang WF, Yue-Wang, Zhou X, Lu T. Li HF, et al. Curr Med Chem. 2010;17(16):1618-34. doi: 10.2174/092986710791111242. Curr Med Chem. 2010. PMID: 20345352 Review.

8

Molecular modeling of exquisitely selective c-Met inhibitors through 3D-QSAR and molecular dynamics simulations.

Yuan H, Zhuang J, Hu S, Li H, Xu J, Hu Y, Xiong X, Chen Y, Lu T. Yuan H, et al. Among authors: li h. J Chem Inf Model. 2014 Sep 22;54(9):2544-54. doi: 10.1021/ci500268s. Epub 2014 Sep 9. J Chem Inf Model. 2014. PMID: 25181449

9

Insight into the key interactions of bromodomain inhibitors based on molecular docking, interaction fingerprinting, molecular dynamics and binding free energy calculation.

Ran T, Zhang Z, Liu K, Lu Y, Li H, Xu J, Xiong X, Zhang Y, Xu A, Lu S, Liu H, Lu T, Chen Y. Ran T, et al. Among authors: li h. Mol Biosyst. 2015 May;11(5):1295-304. doi: 10.1039/c4mb00723a. Mol Biosyst. 2015. PMID: 25758752

10

Small molecule-induced degradation of the full length and V7 truncated variant forms of human androgen receptor.

Dalal K, Morin H, Ban F, Shepherd A, Fernandez M, Tam KJ, Li H, LeBlanc E, Lack N, Prinz H, Rennie PS, Cherkasov A. Dalal K, et al. Among authors: li h. Eur J Med Chem. 2018 Sep 5;157:1164-1173. doi: 10.1016/j.ejmech.2018.08.059. Epub 2018 Aug 24. Eur J Med Chem. 2018. PMID: 30193215

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