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Solution structure of the NaV1.2 C-terminal EF-hand domain.
Miloushev VZ, Levine JA, Arbing MA, Hunt JF, Pitt GS, Palmer AG 3rd. Miloushev VZ, et al. Among authors: pitt gs. J Biol Chem. 2009 Mar 6;284(10):6446-54. doi: 10.1074/jbc.M807401200. Epub 2009 Jan 7. J Biol Chem. 2009. PMID: 19129176 Free PMC article.
Calmodulin mediates Ca2+ sensitivity of sodium channels.
Kim J, Ghosh S, Liu H, Tateyama M, Kass RS, Pitt GS. Kim J, et al. Among authors: pitt gs. J Biol Chem. 2004 Oct 22;279(43):45004-12. doi: 10.1074/jbc.M407286200. Epub 2004 Aug 16. J Biol Chem. 2004. PMID: 15316014 Free article.
Calmodulin binds to the N-terminal domain of the cardiac sodium channel Nav1.5.
Wang Z, Vermij SH, Sottas V, Shestak A, Ross-Kaschitza D, Zaklyazminskaya EV, Hudmon A, Pitt GS, Rougier JS, Abriel H. Wang Z, et al. Among authors: pitt gs. Channels (Austin). 2020 Dec;14(1):268-286. doi: 10.1080/19336950.2020.1805999. Channels (Austin). 2020. PMID: 32815768 Free PMC article.
Fibroblast growth factor homologous factors tune arrhythmogenic late NaV1.5 current in calmodulin binding-deficient channels.
Abrams J, Roybal D, Chakouri N, Katchman AN, Weinberg R, Yang L, Chen BX, Zakharov SI, Hennessey JA, Avula UMR, Diaz J, Wang C, Wan EY, Pitt GS, Ben-Johny M, Marx SO. Abrams J, et al. Among authors: pitt gs. JCI Insight. 2020 Oct 2;5(19):e141736. doi: 10.1172/jci.insight.141736. JCI Insight. 2020. PMID: 32870823 Free PMC article.
123 results