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912 results

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Page 1
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC, Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium; Todd JA, Wallace C, Concannon P, Rich SS. Onengut-Gumuscu S, et al. Among authors: stevens h. Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245. Epub 2015 Mar 9. Nat Genet. 2015. PMID: 25751624 Free PMC article.
Confirmation of novel type 1 diabetes risk loci in families.
Cooper JD, Howson JM, Smyth D, Walker NM, Stevens H, Yang JH, She JX, Eisenbarth GS, Rewers M, Todd JA, Akolkar B, Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Pociot F, Rich SS; Type 1 Diabetes Genetics Consortium. Cooper JD, et al. Among authors: stevens h. Diabetologia. 2012 Apr;55(4):996-1000. doi: 10.1007/s00125-012-2450-3. Epub 2012 Jan 26. Diabetologia. 2012. PMID: 22278338 Free PMC article.
CD226 Gly307Ser association with multiple autoimmune diseases.
Hafler JP, Maier LM, Cooper JD, Plagnol V, Hinks A, Simmonds MJ, Stevens HE, Walker NM, Healy B, Howson JM, Maisuria M, Duley S, Coleman G, Gough SC; International Multiple Sclerosis Genetics Consortium (IMSGC); Worthington J, Kuchroo VK, Wicker LS, Todd JA. Hafler JP, et al. Among authors: stevens he. Genes Immun. 2009 Jan;10(1):5-10. doi: 10.1038/gene.2008.82. Epub 2008 Oct 30. Genes Immun. 2009. PMID: 18971939 Free PMC article.
No association of multiple type 2 diabetes loci with type 1 diabetes.
Raj SM, Howson JM, Walker NM, Cooper JD, Smyth DJ, Field SF, Stevens HE, Todd JA. Raj SM, et al. Among authors: stevens he. Diabetologia. 2009 Oct;52(10):2109-16. doi: 10.1007/s00125-009-1391-y. Epub 2009 May 20. Diabetologia. 2009. PMID: 19455305 Free PMC article.
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.
Barrett JC, Clayton DG, Concannon P, Akolkar B, Cooper JD, Erlich HA, Julier C, Morahan G, Nerup J, Nierras C, Plagnol V, Pociot F, Schuilenburg H, Smyth DJ, Stevens H, Todd JA, Walker NM, Rich SS; Type 1 Diabetes Genetics Consortium. Barrett JC, et al. Among authors: stevens h. Nat Genet. 2009 Jun;41(6):703-7. doi: 10.1038/ng.381. Epub 2009 May 10. Nat Genet. 2009. PMID: 19430480 Free PMC article.
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor.
Ban M, Goris A, Lorentzen AR, Baker A, Mihalova T, Ingram G, Booth DR, Heard RN, Stewart GJ, Bogaert E, Dubois B, Harbo HF, Celius EG, Spurkland A, Strange R, Hawkins C, Robertson NP, Dudbridge F, Wason J, De Jager PL, Hafler D, Rioux JD, Ivinson AJ, McCauley JL, Pericak-Vance M, Oksenberg JR, Hauser SL, Sexton D, Haines J, Sawcer S; Wellcome Trust Case-Control Consortium (WTCCC); Compston A. Ban M, et al. Eur J Hum Genet. 2009 Oct;17(10):1309-13. doi: 10.1038/ejhg.2009.41. Epub 2009 Mar 18. Eur J Hum Genet. 2009. PMID: 19293837 Free PMC article.
Combined effects of three independent SNPs greatly increase the risk estimate for RA at 6q23.
Orozco G, Hinks A, Eyre S, Ke X, Gibbons LJ, Bowes J, Flynn E, Martin P; Wellcome Trust Case Control Consortium; YEAR consortium; Wilson AG, Bax DE, Morgan AW, Emery P, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Thomson W, Barton A, Worthington J. Orozco G, et al. Hum Mol Genet. 2009 Jul 15;18(14):2693-9. doi: 10.1093/hmg/ddp193. Epub 2009 May 5. Hum Mol Genet. 2009. PMID: 19417005 Free PMC article.
912 results