Der CJ - Search Results

1

Aberrant receptor internalization and enhanced FRS2-dependent signaling contribute to the transforming activity of the fibroblast growth factor receptor 2 IIIb C3 isoform.

Cha JY, Maddileti S, Mitin N, Harden TK, Der CJ. Cha JY, et al. Among authors: der cj. J Biol Chem. 2009 Mar 6;284(10):6227-40. doi: 10.1074/jbc.M803998200. Epub 2008 Dec 22. J Biol Chem. 2009. PMID: 19103595 Free PMC article.

2

Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct.

Khosravi-Far R, Clark GJ, Abe K, Cox AD, McLain T, Lutz RJ, Sinensky M, Der CJ. Khosravi-Far R, et al. Among authors: der cj. J Biol Chem. 1992 Dec 5;267(34):24363-8. J Biol Chem. 1992. PMID: 1332953 Free article.

3

Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes.

Lerner EC, Qian Y, Blaskovich MA, Fossum RD, Vogt A, Sun J, Cox AD, Der CJ, Hamilton AD, Sebti SM. Lerner EC, et al. Among authors: der cj. J Biol Chem. 1995 Nov 10;270(45):26802-6. doi: 10.1074/jbc.270.45.26802. J Biol Chem. 1995. PMID: 7592920 Free article.

4

Two distinct Raf domains mediate interaction with Ras.

Brtva TR, Drugan JK, Ghosh S, Terrell RS, Campbell-Burk S, Bell RM, Der CJ. Brtva TR, et al. Among authors: der cj. J Biol Chem. 1995 Apr 28;270(17):9809-12. doi: 10.1074/jbc.270.17.9809. J Biol Chem. 1995. PMID: 7730360 Free article.

5

Identification and characterization of Src SH3 ligands from phage-displayed random peptide libraries.

Sparks AB, Quilliam LA, Thorn JM, Der CJ, Kay BK. Sparks AB, et al. Among authors: der cj. J Biol Chem. 1994 Sep 30;269(39):23853-6. J Biol Chem. 1994. PMID: 7929027 Free article.

6

The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation.

Cox AD, Garcia AM, Westwick JK, Kowalczyk JJ, Lewis MD, Brenner DA, Der CJ. Cox AD, et al. Among authors: der cj. J Biol Chem. 1994 Jul 29;269(30):19203-6. J Biol Chem. 1994. PMID: 8034681 Free article.

7

The carboxyl-terminal CXXX sequence of Gi alpha, but not Rab5 or Rab11, supports Ras processing and transforming activity.

Cox AD, Graham SM, Solski PA, Buss JE, Der CJ. Cox AD, et al. Among authors: der cj. J Biol Chem. 1993 Jun 5;268(16):11548-52. J Biol Chem. 1993. PMID: 8505289 Free article.

8

Ras interaction with two distinct binding domains in Raf-1 may be required for Ras transformation.

Drugan JK, Khosravi-Far R, White MA, Der CJ, Sung YJ, Hwang YW, Campbell SL. Drugan JK, et al. Among authors: der cj. J Biol Chem. 1996 Jan 5;271(1):233-7. doi: 10.1074/jbc.271.1.233. J Biol Chem. 1996. PMID: 8550565 Free article.

9

Oncogenic Neu/ErbB-2 increases ets, AP-1, and NF-kappaB-dependent gene expression, and inhibiting ets activation blocks Neu-mediated cellular transformation.

Galang CK, García-Ramírez J, Solski PA, Westwick JK, Der CJ, Neznanov NN, Oshima RG, Hauser CA. Galang CK, et al. Among authors: der cj. J Biol Chem. 1996 Apr 5;271(14):7992-8. doi: 10.1074/jbc.271.14.7992. J Biol Chem. 1996. PMID: 8626480 Free article.

10

Binding specificity and mutational analysis of the phosphotyrosine binding domain of the brain-specific adaptor protein ShcC.

O'Bryan JP, Martin CB, Songyang Z, Cantley LC, Der CJ. O'Bryan JP, et al. Among authors: der cj. J Biol Chem. 1996 May 17;271(20):11787-91. doi: 10.1074/jbc.271.20.11787. J Biol Chem. 1996. PMID: 8662772 Free article.

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