Kager L - Search Results

1

Pharmacogenetics in acute lymphoblastic leukemia.

Cheok MH, Pottier N, Kager L, Evans WE. Cheok MH, et al. Among authors: kager l. Semin Hematol. 2009 Jan;46(1):39-51. doi: 10.1053/j.seminhematol.2008.09.002. Semin Hematol. 2009. PMID: 19100367 Free PMC article. Review.

2

Pharmacogenomics of acute lymphoblastic leukemia.

Kager L, Evans WE. Kager L, et al. Curr Opin Hematol. 2006 Jul;13(4):260-5. doi: 10.1097/01.moh.0000231424.46148.f9. Curr Opin Hematol. 2006. PMID: 16755223 Review.

3

In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile.

Sorich MJ, Pottier N, Pei D, Yang W, Kager L, Stocco G, Cheng C, Panetta JC, Pui CH, Relling MV, Cheok MH, Evans WE. Sorich MJ, et al. Among authors: kager l. PLoS Med. 2008 Apr 15;5(4):e83. doi: 10.1371/journal.pmed.0050083. PLoS Med. 2008. PMID: 18416598 Free PMC article.

4

Acute lymphoblastic leukemia with TEL-AML1 fusion has lower expression of genes involved in purine metabolism and lower de novo purine synthesis.

Zaza G, Yang W, Kager L, Cheok M, Downing J, Pui CH, Cheng C, Relling MV, Evans WE. Zaza G, et al. Among authors: kager l. Blood. 2004 Sep 1;104(5):1435-41. doi: 10.1182/blood-2003-12-4306. Epub 2004 May 13. Blood. 2004. PMID: 15142881 Free article.

5

Folate pathway gene expression differs in subtypes of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics.

Kager L, Cheok M, Yang W, Zaza G, Cheng Q, Panetta JC, Pui CH, Downing JR, Relling MV, Evans WE. Kager L, et al. J Clin Invest. 2005 Jan;115(1):110-7. doi: 10.1172/JCI22477. J Clin Invest. 2005. PMID: 15630450 Free PMC article.

6

High-dose methotrexate: the rationale..

Cheok MH, Evans WE, Kager L. Cheok MH, et al. Among authors: kager l. J Pediatr Hematol Oncol. 2009 Mar;31(3):224-5. doi: 10.1097/MPH.0b013e318196a2a6. J Pediatr Hematol Oncol. 2009. PMID: 19262256 No abstract available.

7

Antileukemic drug effects in childhood acute lymphoblastic leukemia.

Pottier N, Cheok M, Kager L. Pottier N, et al. Among authors: kager l. Expert Rev Clin Pharmacol. 2008 May;1(3):401-13. doi: 10.1586/17512433.1.3.401. Expert Rev Clin Pharmacol. 2008. PMID: 24422694

8

A substrate specific functional polymorphism of human gamma-glutamyl hydrolase alters catalytic activity and methotrexate polyglutamate accumulation in acute lymphoblastic leukaemia cells.

Cheng Q, Wu B, Kager L, Panetta JC, Zheng J, Pui CH, Relling MV, Evans WE. Cheng Q, et al. Among authors: kager l. Pharmacogenetics. 2004 Aug;14(8):557-67. doi: 10.1097/01.fpc.0000114761.78957.7e. Pharmacogenetics. 2004. PMID: 15284538

9

Genomic strategies to improve outcome and individualize therapy in cancer: the paradigm of childhood acute lymphoblastic leukemia.

Kager L. Kager L. J BUON. 2009 Sep;14 Suppl 1:S181-6. J BUON. 2009. PMID: 19785064 Review.

10

PharmGKB summary: methotrexate pathway.

Mikkelsen TS, Thorn CF, Yang JJ, Ulrich CM, French D, Zaza G, Dunnenberger HM, Marsh S, McLeod HL, Giacomini K, Becker ML, Gaedigk R, Leeder JS, Kager L, Relling MV, Evans W, Klein TE, Altman RB. Mikkelsen TS, et al. Among authors: kager l. Pharmacogenet Genomics. 2011 Oct;21(10):679-86. doi: 10.1097/FPC.0b013e328343dd93. Pharmacogenet Genomics. 2011. PMID: 21317831 Free PMC article. No abstract available.

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