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Page 1
Structure-function relationship of tumor necrosis factor (TNF) and its receptor interaction based on 3D structural analysis of a fully active TNFR1-selective TNF mutant.
Mukai Y, Shibata H, Nakamura T, Yoshioka Y, Abe Y, Nomura T, Taniai M, Ohta T, Ikemizu S, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y. Mukai Y, et al. Among authors: ikemizu s. J Mol Biol. 2009 Jan 30;385(4):1221-9. doi: 10.1016/j.jmb.2008.11.053. Epub 2008 Dec 6. J Mol Biol. 2009. PMID: 19084540
Optimal site-specific PEGylation of mutant TNF-alpha improves its antitumor potency.
Yoshioka Y, Tsutsumi Y, Ikemizu S, Yamamoto Y, Shibata H, Nishibata T, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Nagata S, Yamagata Y, Mayumi T. Yoshioka Y, et al. Among authors: ikemizu s. Biochem Biophys Res Commun. 2004 Mar 19;315(4):808-14. doi: 10.1016/j.bbrc.2004.01.125. Biochem Biophys Res Commun. 2004. PMID: 14985084
Functionalization of tumor necrosis factor-alpha using phage display technique and PEGylation improves its antitumor therapeutic window.
Shibata H, Yoshioka Y, Ikemizu S, Kobayashi K, Yamamoto Y, Mukai Y, Okamoto T, Taniai M, Kawamura M, Abe Y, Nakagawa S, Hayakawa T, Nagata S, Yamagata Y, Mayumi T, Kamada H, Tsutsumi Y. Shibata H, et al. Among authors: ikemizu s. Clin Cancer Res. 2004 Dec 15;10(24):8293-300. doi: 10.1158/1078-0432.CCR-04-0770. Clin Cancer Res. 2004. PMID: 15623605
Preparation, crystallization and preliminary X-ray diffraction analysis of the DNA-binding domain of the Ets transcription factor in complex with target DNA.
Suwa Y, Nakamura T, Toma S, Ikemizu S, Kai H, Yamagata Y. Suwa Y, et al. Among authors: ikemizu s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 Mar 1;64(Pt 3):171-4. doi: 10.1107/S1744309108002662. Epub 2008 Feb 23. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18323600 Free PMC article.
Crystallization and preliminary X-ray analysis of human MTH1 with a homogeneous N-terminus.
Koga Y, Inazato M, Nakamura T, Hashikawa C, Chirifu M, Michi A, Yamashita T, Toma S, Kuniyasu A, Ikemizu S, Nakabeppu Y, Yamagata Y. Koga Y, et al. Among authors: ikemizu s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jan 1;69(Pt 1):45-8. doi: 10.1107/S1744309112048002. Epub 2012 Dec 20. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID: 23295485 Free PMC article.
Crystallization and preliminary X-ray analysis of human MTH1 complexed with two oxidized nucleotides, 8-oxo-dGMP and 2-oxo-dATP.
Nakamura T, Kitaguchi Y, Miyazawa M, Kamiya H, Toma S, Ikemizu S, Shirakawa M, Nakabeppu Y, Yamagata Y. Nakamura T, et al. Among authors: ikemizu s. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Dec 1;62(Pt 12):1283-5. doi: 10.1107/S1744309106049529. Epub 2006 Nov 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006. PMID: 17142918 Free PMC article.
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