Deas E - Search Results

1

What have PINK1 and HtrA2 genes told us about the role of mitochondria in Parkinson's disease?

Plun-Favreau H, Gandhi S, Wood-Kaczmar A, Deas E, Yao Z, Wood NW. Plun-Favreau H, et al. Among authors: deas e. Ann N Y Acad Sci. 2008 Dec;1147:30-6. doi: 10.1196/annals.1427.032. Ann N Y Acad Sci. 2008. PMID: 19076428

2

HtrA2 deficiency causes mitochondrial uncoupling through the F₁F₀-ATP synthase and consequent ATP depletion.

Plun-Favreau H, Burchell VS, Holmström KM, Yao Z, Deas E, Cain K, Fedele V, Moisoi N, Campanella M, Miguel Martins L, Wood NW, Gourine AV, Abramov AY. Plun-Favreau H, et al. Among authors: deas e. Cell Death Dis. 2012 Jun 28;3(6):e335. doi: 10.1038/cddis.2012.77. Cell Death Dis. 2012. PMID: 22739987 Free PMC article.

3

A heterozygous effect for PINK1 mutations in Parkinson's disease?

Abou-Sleiman PM, Muqit MM, McDonald NQ, Yang YX, Gandhi S, Healy DG, Harvey K, Harvey RJ, Deas E, Bhatia K, Quinn N, Lees A, Latchman DS, Wood NW. Abou-Sleiman PM, et al. Among authors: deas e. Ann Neurol. 2006 Oct;60(4):414-9. doi: 10.1002/ana.20960. Ann Neurol. 2006. PMID: 16969854

4

The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.

Plun-Favreau H, Klupsch K, Moisoi N, Gandhi S, Kjaer S, Frith D, Harvey K, Deas E, Harvey RJ, McDonald N, Wood NW, Martins LM, Downward J. Plun-Favreau H, et al. Among authors: deas e. Nat Cell Biol. 2007 Nov;9(11):1243-52. doi: 10.1038/ncb1644. Epub 2007 Sep 30. Nat Cell Biol. 2007. PMID: 17906618

5

PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons.

Wood-Kaczmar A, Gandhi S, Yao Z, Abramov AY, Miljan EA, Keen G, Stanyer L, Hargreaves I, Klupsch K, Deas E, Downward J, Mansfield L, Jat P, Taylor J, Heales S, Duchen MR, Latchman D, Tabrizi SJ, Wood NW. Wood-Kaczmar A, et al. Among authors: deas e. PLoS One. 2008 Jun 18;3(6):e2455. doi: 10.1371/journal.pone.0002455. PLoS One. 2008. PMID: 18560593 Free PMC article.

6

PINK1-associated Parkinson's disease is caused by neuronal vulnerability to calcium-induced cell death.

Gandhi S, Wood-Kaczmar A, Yao Z, Plun-Favreau H, Deas E, Klupsch K, Downward J, Latchman DS, Tabrizi SJ, Wood NW, Duchen MR, Abramov AY. Gandhi S, et al. Among authors: deas e. Mol Cell. 2009 Mar 13;33(5):627-38. doi: 10.1016/j.molcel.2009.02.013. Mol Cell. 2009. PMID: 19285945 Free PMC article.

7

PINK1 function in health and disease.

Deas E, Plun-Favreau H, Wood NW. Deas E, et al. EMBO Mol Med. 2009 Jun;1(3):152-65. doi: 10.1002/emmm.200900024. EMBO Mol Med. 2009. PMID: 20049715 Free PMC article. Review.

8

Targeting mitochondrial dysfunction in neurodegenerative disease: Part I.

Burchell VS, Gandhi S, Deas E, Wood NW, Abramov AY, Plun-Favreau H. Burchell VS, et al. Among authors: deas e. Expert Opin Ther Targets. 2010 Apr;14(4):369-85. doi: 10.1517/14728221003652489. Expert Opin Ther Targets. 2010. PMID: 20184395 Review.

9

Targeting mitochondrial dysfunction in neurodegenerative disease: Part II.

Burchell VS, Gandhi S, Deas E, Wood NW, Abramov AY, Plun-Favreau H. Burchell VS, et al. Among authors: deas e. Expert Opin Ther Targets. 2010 May;14(5):497-511. doi: 10.1517/14728221003730434. Expert Opin Ther Targets. 2010. PMID: 20334487 Review.

10

Mitophagy and Parkinson's disease: the PINK1-parkin link.

Deas E, Wood NW, Plun-Favreau H. Deas E, et al. Biochim Biophys Acta. 2011 Apr;1813(4):623-33. doi: 10.1016/j.bbamcr.2010.08.007. Epub 2010 Aug 21. Biochim Biophys Acta. 2011. PMID: 20736035 Free PMC article. Review.

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