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A highly invasive human glioblastoma pre-clinical model for testing therapeutics.
Xie Q, Thompson R, Hardy K, DeCamp L, Berghuis B, Sigler R, Knudsen B, Cottingham S, Zhao P, Dykema K, Cao B, Resau J, Hay R, Vande Woude GF. Xie Q, et al. Among authors: dykema k. J Transl Med. 2008 Dec 3;6:77. doi: 10.1186/1479-5876-6-77. J Transl Med. 2008. PMID: 19055779 Free PMC article.
Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer.
Graveel CR, DeGroot JD, Su Y, Koeman J, Dykema K, Leung S, Snider J, Davies SR, Swiatek PJ, Cottingham S, Watson MA, Ellis MJ, Sigler RE, Furge KA, Vande Woude GF. Graveel CR, et al. Among authors: dykema k. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):12909-14. doi: 10.1073/pnas.0810403106. Epub 2009 Jun 30. Proc Natl Acad Sci U S A. 2009. PMID: 19567831 Free PMC article.
Overexpression of HGF Promotes HBV-Induced Hepatocellular Carcinoma Progression and Is an Effective Indicator for Met-Targeting Therapy.
Xie Q, Su Y, Dykema K, Johnson J, Koeman J, De Giorgi V, Huang A, Schlegel R, Essenburg C, Kang L, Iwaya K, Seki S, Khoo SK, Zhang B, Buonaguro F, Marincola FM, Furge K, Vande Woude GF, Shinomiya N. Xie Q, et al. Among authors: dykema k. Genes Cancer. 2013 Jul;4(7-8):247-60. doi: 10.1177/1947601913501075. Genes Cancer. 2013. PMID: 24167653 Free PMC article.
Chromosome instability drives phenotypic switching to metastasis.
Gao C, Su Y, Koeman J, Haak E, Dykema K, Essenberg C, Hudson E, Petillo D, Khoo SK, Vande Woude GF. Gao C, et al. Among authors: dykema k. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14793-14798. doi: 10.1073/pnas.1618215113. Epub 2016 Dec 5. Proc Natl Acad Sci U S A. 2016. PMID: 27930335 Free PMC article.
Disruption of tubular Flcn expression as a mouse model for renal tumor induction.
Chen J, Huang D, Rubera I, Futami K, Wang P, Zickert P, Khoo SK, Dykema K, Zhao P, Petillo D, Cao B, Zhang Z, Si S, Schoen SR, Yang XJ, Zhou M, Xiao GQ, Wu G, Nordenskjöld M, Tauc M, Williams BO, Furge KA, Teh BT. Chen J, et al. Among authors: dykema k. Kidney Int. 2015 Nov;88(5):1057-69. doi: 10.1038/ki.2015.177. Epub 2015 Jun 17. Kidney Int. 2015. PMID: 26083655 Free article.
57 results