Miller ML - Search Results

1

Knock-in mouse lines expressing either mitochondrial or microsomal CYP1A1: differing responses to dietary benzo[a]pyrene as proof of principle.

Dong H, Dalton TP, Miller ML, Chen Y, Uno S, Shi Z, Shertzer HG, Bansal S, Avadhani NG, Nebert DW. Dong H, et al. Among authors: miller ml. Mol Pharmacol. 2009 Mar;75(3):555-67. doi: 10.1124/mol.108.051888. Epub 2008 Dec 1. Mol Pharmacol. 2009. PMID: 19047483 Free PMC article.

2

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.

Uno S, Dalton TP, Sinclair PR, Gorman N, Wang B, Smith AG, Miller ML, Shertzer HG, Nebert DW. Uno S, et al. Among authors: miller ml. Toxicol Appl Pharmacol. 2004 May 1;196(3):410-21. doi: 10.1016/j.taap.2004.01.014. Toxicol Appl Pharmacol. 2004. PMID: 15094312

3

Oral exposure to benzo[a]pyrene in the mouse: detoxication by inducible cytochrome P450 is more important than metabolic activation.

Uno S, Dalton TP, Derkenne S, Curran CP, Miller ML, Shertzer HG, Nebert DW. Uno S, et al. Among authors: miller ml. Mol Pharmacol. 2004 May;65(5):1225-37. doi: 10.1124/mol.65.5.1225. Mol Pharmacol. 2004. PMID: 15102951

4

Oral benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and clearance rate.

Uno S, Dalton TP, Dragin N, Curran CP, Derkenne S, Miller ML, Shertzer HG, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: miller ml. Mol Pharmacol. 2006 Apr;69(4):1103-14. doi: 10.1124/mol.105.021501. Epub 2005 Dec 23. Mol Pharmacol. 2006. PMID: 16377763

5

For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential.

Dragin N, Dalton TP, Miller ML, Shertzer HG, Nebert DW. Dragin N, et al. Among authors: miller ml. J Biol Chem. 2006 Jul 7;281(27):18591-600. doi: 10.1074/jbc.M601159200. Epub 2006 Apr 24. J Biol Chem. 2006. PMID: 16636061 Free article.

6

Basal and inducible CYP1 mRNA quantitation and protein localization throughout the mouse gastrointestinal tract.

Uno S, Dragin N, Miller ML, Dalton TP, Gonzalez FJ, Nebert DW. Uno S, et al. Among authors: miller ml. Free Radic Biol Med. 2008 Feb 15;44(4):570-83. doi: 10.1016/j.freeradbiomed.2007.10.044. Epub 2007 Nov 12. Free Radic Biol Med. 2008. PMID: 17997381 Free PMC article.

7

Oral benzo[a]pyrene-induced cancer: two distinct types in different target organs depend on the mouse Cyp1 genotype.

Shi Z, Dragin N, Miller ML, Stringer KF, Johansson E, Chen J, Uno S, Gonzalez FJ, Rubio CA, Nebert DW. Shi Z, et al. Among authors: miller ml. Int J Cancer. 2010 Nov 15;127(10):2334-50. doi: 10.1002/ijc.25222. Int J Cancer. 2010. PMID: 20127859 Free PMC article.

8

Organ-specific roles of CYP1A1 during detoxication of dietary benzo[a]pyrene.

Shi Z, Dragin N, Gálvez-Peralta M, Jorge-Nebert LF, Miller ML, Wang B, Nebert DW. Shi Z, et al. Among authors: miller ml. Mol Pharmacol. 2010 Jul;78(1):46-57. doi: 10.1124/mol.110.063438. Epub 2010 Apr 6. Mol Pharmacol. 2010. PMID: 20371670 Free PMC article.

9

Oral benzo[a]pyrene in Cyp1a1/1b1(-/-) double-knockout mice: Microarray analysis during squamous cell carcinoma formation in preputial gland duct.

Gálvez-Peralta M, Shi Z, Chen J, Miller ML, Nebert DW. Gálvez-Peralta M, et al. Among authors: miller ml. Int J Cancer. 2013 May 1;132(9):2065-75. doi: 10.1002/ijc.27897. Epub 2012 Dec 4. Int J Cancer. 2013. PMID: 23047765

10

Pharmacological rescue of the 14CoS/14CoS mouse: hepatocyte apoptosis is likely caused by endogenous oxidative stress.

Dieter MZ, Freshwater SL, Miller ML, Shertzer HG, Dalton TP, Nebert DW. Dieter MZ, et al. Among authors: miller ml. Free Radic Biol Med. 2003 Aug 15;35(4):351-67. doi: 10.1016/s0891-5849(03)00273-9. Free Radic Biol Med. 2003. PMID: 12899938

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