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SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging.
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, Wright SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA. Oberdoerffer P, et al. Among authors: sinclair da. Cell. 2008 Nov 28;135(5):907-18. doi: 10.1016/j.cell.2008.10.025. Cell. 2008. PMID: 19041753 Free PMC article.
Molecular mechanisms of yeast aging.
Sinclair DA, Mills K, Guarente L. Sinclair DA, et al. Trends Biochem Sci. 1998 Apr;23(4):131-4. doi: 10.1016/s0968-0004(98)01188-8. Trends Biochem Sci. 1998. PMID: 9584615 Review.
Aging in Saccharomyces cerevisiae.
Sinclair D, Mills K, Guarente L. Sinclair D, et al. Annu Rev Microbiol. 1998;52:533-60. doi: 10.1146/annurev.micro.52.1.533. Annu Rev Microbiol. 1998. PMID: 9891807 Review.
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase.
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, Hu LS, Cheng HL, Jedrychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME. Brunet A, et al. Among authors: sinclair da. Science. 2004 Mar 26;303(5666):2011-5. doi: 10.1126/science.1094637. Epub 2004 Feb 19. Science. 2004. PMID: 14976264
Design and synthesis of compounds that extend yeast replicative lifespan.
Yang H, Baur JA, Chen A, Miller C, Adams JK, Kisielewski A, Howitz KT, Zipkin RE, Sinclair DA. Yang H, et al. Among authors: sinclair da. Aging Cell. 2007 Feb;6(1):35-43. doi: 10.1111/j.1474-9726.2006.00259.x. Epub 2006 Dec 5. Aging Cell. 2007. PMID: 17156081 Free PMC article.
283 results