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Page 1
4-hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity.
Pizzimenti S, Menegatti E, Berardi D, Toaldo C, Pettazzoni P, Minelli R, Giglioni B, Cerbone A, Dianzani MU, Ferretti C, Barrera G. Pizzimenti S, et al. Among authors: pettazzoni p. J Nutr Biochem. 2010 Sep;21(9):818-26. doi: 10.1016/j.jnutbio.2009.06.005. Epub 2009 Sep 3. J Nutr Biochem. 2010. PMID: 19733043
Induction of cell cycle arrest and DNA damage by the HDAC inhibitor panobinostat (LBH589) and the lipid peroxidation end product 4-hydroxynonenal in prostate cancer cells.
Pettazzoni P, Pizzimenti S, Toaldo C, Sotomayor P, Tagliavacca L, Liu S, Wang D, Minelli R, Ellis L, Atadja P, Ciamporcero E, Dianzani MU, Barrera G, Pili R. Pettazzoni P, et al. Free Radic Biol Med. 2011 Jan 15;50(2):313-22. doi: 10.1016/j.freeradbiomed.2010.11.011. Epub 2010 Nov 13. Free Radic Biol Med. 2011. PMID: 21078383
The inclusion complex of 4-hydroxynonenal with a polymeric derivative of β-cyclodextrin enhances the antitumoral efficacy of the aldehyde in several tumor cell lines and in a three-dimensional human melanoma model.
Pizzimenti S, Ciamporcero E, Pettazzoni P, Osella-Abate S, Novelli M, Toaldo C, Husse M, Daga M, Minelli R, Bisazza A, Ferruti P, Ranucci E, Grazia Bernengo M, Dianzani C, Biasi F, Cavalli R, Barrera G. Pizzimenti S, et al. Among authors: pettazzoni p. Free Radic Biol Med. 2013 Dec;65:765-777. doi: 10.1016/j.freeradbiomed.2013.06.035. Epub 2013 Jun 26. Free Radic Biol Med. 2013. PMID: 23811007 Free article.
Exposure of HL-60 human leukaemic cells to 4-hydroxynonenal promotes the formation of adduct(s) with alpha-enolase devoid of plasminogen binding activity.
Gentile F, Pizzimenti S, Arcaro A, Pettazzoni P, Minelli R, D'Angelo D, Mamone G, Ferranti P, Toaldo C, Cetrangolo G, Formisano S, Dianzani MU, Uchida K, Dianzani C, Barrera G. Gentile F, et al. Among authors: pettazzoni p. Biochem J. 2009 Aug 13;422(2):285-94. doi: 10.1042/BJ20090564. Biochem J. 2009. PMID: 19508232
PPARgamma ligands inhibit telomerase activity and hTERT expression through modulation of the Myc/Mad/Max network in colon cancer cells.
Toaldo C, Pizzimenti S, Cerbone A, Pettazzoni P, Menegatti E, Daniela B, Minelli R, Giglioni B, Dianzani MU, Ferretti C, Barrera G. Toaldo C, et al. Among authors: pettazzoni p. J Cell Mol Med. 2010 Jun;14(6A):1347-57. doi: 10.1111/j.1582-4934.2009.00966.x. Epub 2009 Nov 13. J Cell Mol Med. 2010. PMID: 19912441 Free PMC article.
Rosiglitazone and AS601245 decrease cell adhesion and migration through modulation of specific gene expression in human colon cancer cells.
Cerbone A, Toaldo C, Minelli R, Ciamporcero E, Pizzimenti S, Pettazzoni P, Roma G, Dianzani MU, Ullio C, Ferretti C, Dianzani C, Barrera G. Cerbone A, et al. Among authors: pettazzoni p. PLoS One. 2012;7(6):e40149. doi: 10.1371/journal.pone.0040149. Epub 2012 Jun 28. PLoS One. 2012. PMID: 22761953 Free PMC article.
60 results