Luehrs DC - Search Results

1

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations.

Maarouf CL, Daugs ID, Spina S, Vidal R, Kokjohn TA, Patton RL, Kalback WM, Luehrs DC, Walker DG, Castaño EM, Beach TG, Ghetti B, Roher AE. Maarouf CL, et al. Among authors: luehrs dc. Mol Neurodegener. 2008 Nov 20;3:20. doi: 10.1186/1750-1326-3-20. Mol Neurodegener. 2008. PMID: 19021905 Free PMC article.

2

Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's disease.

Van Vickle GD, Esh CL, Kokjohn TA, Patton RL, Kalback WM, Luehrs DC, Beach TG, Newel AJ, Lopera F, Ghetti B, Vidal R, Castaño EM, Roher AE. Van Vickle GD, et al. Among authors: luehrs dc. Mol Med. 2008 Mar-Apr;14(3-4):184-94. doi: 10.2119/2007-00094.vanvickle. Mol Med. 2008. PMID: 18317569 Free PMC article.

3

The biochemical aftermath of anti-amyloid immunotherapy.

Maarouf CL, Daugs ID, Kokjohn TA, Kalback WM, Patton RL, Luehrs DC, Masliah E, Nicoll JA, Sabbagh MN, Beach TG, Castaño EM, Roher AE. Maarouf CL, et al. Among authors: luehrs dc. Mol Neurodegener. 2010 Oct 7;5:39. doi: 10.1186/1750-1326-5-39. Mol Neurodegener. 2010. PMID: 20929585 Free PMC article.

4

Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease.

Roher AE, Weiss N, Kokjohn TA, Kuo YM, Kalback W, Anthony J, Watson D, Luehrs DC, Sue L, Walker D, Emmerling M, Goux W, Beach T. Roher AE, et al. Among authors: luehrs dc. Biochemistry. 2002 Sep 17;41(37):11080-90. doi: 10.1021/bi026173d. Biochemistry. 2002. PMID: 12220172

5

Cortical and leptomeningeal cerebrovascular amyloid and white matter pathology in Alzheimer's disease.

Roher AE, Kuo YM, Esh C, Knebel C, Weiss N, Kalback W, Luehrs DC, Childress JL, Beach TG, Weller RO, Kokjohn TA. Roher AE, et al. Among authors: luehrs dc. Mol Med. 2003 Mar-Apr;9(3-4):112-22. Mol Med. 2003. PMID: 12865947 Free PMC article.

6

Circle of willis atherosclerosis is a risk factor for sporadic Alzheimer's disease.

Roher AE, Esh C, Kokjohn TA, Kalback W, Luehrs DC, Seward JD, Sue LI, Beach TG. Roher AE, et al. Among authors: luehrs dc. Arterioscler Thromb Vasc Biol. 2003 Nov 1;23(11):2055-62. doi: 10.1161/01.ATV.0000095973.42032.44. Epub 2003 Sep 25. Arterioscler Thromb Vasc Biol. 2003. PMID: 14512367

7

The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates.

Roher AE, Kokjohn TA, Esh C, Weiss N, Childress J, Kalback W, Luehrs DC, Lopez J, Brune D, Kuo YM, Farlow M, Murrell J, Vidal R, Ghetti B. Roher AE, et al. Among authors: luehrs dc. J Biol Chem. 2004 Feb 13;279(7):5829-36. doi: 10.1074/jbc.M311380200. Epub 2003 Nov 26. J Biol Chem. 2004. PMID: 14645225 Free article.

8

Atherosclerosis, vascular amyloidosis and brain hypoperfusion in the pathogenesis of sporadic Alzheimer's disease.

Kalback W, Esh C, Castaño EM, Rahman A, Kokjohn T, Luehrs DC, Sue L, Cisneros R, Gerber F, Richardson C, Bohrmann B, Walker DG, Beach TG, Roher AE. Kalback W, et al. Among authors: luehrs dc. Neurol Res. 2004 Jul;26(5):525-39. doi: 10.1179/016164104225017668. Neurol Res. 2004. PMID: 15265270 Review.

9

Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis.

Patton RL, Kalback WM, Esh CL, Kokjohn TA, Van Vickle GD, Luehrs DC, Kuo YM, Lopez J, Brune D, Ferrer I, Masliah E, Newel AJ, Beach TG, Castaño EM, Roher AE. Patton RL, et al. Among authors: luehrs dc. Am J Pathol. 2006 Sep;169(3):1048-63. doi: 10.2353/ajpath.2006.060269. Am J Pathol. 2006. PMID: 16936277 Free PMC article.

10

TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation.

Van Vickle GD, Esh CL, Kalback WM, Patton RL, Luehrs DC, Kokjohn TA, Fifield FG, Fraser PE, Westaway D, McLaurin J, Lopez J, Brune D, Newel AJ, Poston M, Beach TG, Roher AE. Van Vickle GD, et al. Among authors: luehrs dc. Biochemistry. 2007 Sep 11;46(36):10317-27. doi: 10.1021/bi700951u. Epub 2007 Aug 18. Biochemistry. 2007. PMID: 17705508

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