Hjelmeland AB - Search Results

1

c-Myc is required for maintenance of glioma cancer stem cells.

Wang J, Wang H, Li Z, Wu Q, Lathia JD, McLendon RE, Hjelmeland AB, Rich JN. Wang J, et al. Among authors: hjelmeland ab. PLoS One. 2008;3(11):e3769. doi: 10.1371/journal.pone.0003769. Epub 2008 Nov 20. PLoS One. 2008. PMID: 19020659 Free PMC article.

2

SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility.

Hjelmeland MD, Hjelmeland AB, Sathornsumetee S, Reese ED, Herbstreith MH, Laping NJ, Friedman HS, Bigner DD, Wang XF, Rich JN. Hjelmeland MD, et al. Among authors: hjelmeland ab. Mol Cancer Ther. 2004 Jun;3(6):737-45. Mol Cancer Ther. 2004. PMID: 15210860

3

Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.

Hjelmeland AB, Hjelmeland MD, Shi Q, Hart JL, Bigner DD, Wang XF, Kontos CD, Rich JN. Hjelmeland AB, et al. Among authors: hjelmeland md. Cancer Res. 2005 Dec 15;65(24):11276-81. doi: 10.1158/0008-5472.CAN-05-3016. Cancer Res. 2005. PMID: 16357132

4

Stem cell-like glioma cells promote tumor angiogenesis through vascular endothelial growth factor.

Bao S, Wu Q, Sathornsumetee S, Hao Y, Li Z, Hjelmeland AB, Shi Q, McLendon RE, Bigner DD, Rich JN. Bao S, et al. Among authors: hjelmeland ab. Cancer Res. 2006 Aug 15;66(16):7843-8. doi: 10.1158/0008-5472.CAN-06-1010. Cancer Res. 2006. PMID: 16912155

5

AAL881, a novel small molecule inhibitor of RAF and vascular endothelial growth factor receptor activities, blocks the growth of malignant glioma.

Sathornsumetee S, Hjelmeland AB, Keir ST, McLendon RE, Batt D, Ramsey T, Yusuff N, Rasheed BK, Kieran MW, Laforme A, Bigner DD, Friedman HS, Rich JN. Sathornsumetee S, et al. Among authors: hjelmeland ab. Cancer Res. 2006 Sep 1;66(17):8722-30. doi: 10.1158/0008-5472.CAN-06-0284. Cancer Res. 2006. PMID: 16951188

6

APOE4-VLDL inhibits the HDL-activated phosphatidylinositol 3-kinase/Akt Pathway via the phosphoinositol phosphatase SHIP2.

DeKroon R, Robinette JB, Hjelmeland AB, Wiggins E, Blackwell M, Mihovilovic M, Fujii M, York J, Hart J, Kontos C, Rich J, Strittmatter WJ. DeKroon R, et al. Among authors: hjelmeland ab. Circ Res. 2006 Oct 13;99(8):829-36. doi: 10.1161/01.RES.0000245479.03190.9f. Epub 2006 Sep 14. Circ Res. 2006. PMID: 16973905

7

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response.

Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Bao S, et al. Among authors: hjelmeland ab. Nature. 2006 Dec 7;444(7120):756-60. doi: 10.1038/nature05236. Epub 2006 Oct 18. Nature. 2006. PMID: 17051156

8

Targeting SPARC expression decreases glioma cellular survival and invasion associated with reduced activities of FAK and ILK kinases.

Shi Q, Bao S, Song L, Wu Q, Bigner DD, Hjelmeland AB, Rich JN. Shi Q, et al. Among authors: hjelmeland ab. Oncogene. 2007 Jun 14;26(28):4084-94. doi: 10.1038/sj.onc.1210181. Epub 2007 Jan 8. Oncogene. 2007. PMID: 17213807

9

A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth.

Shi Q, Hjelmeland AB, Keir ST, Song L, Wickman S, Jackson D, Ohmori O, Bigner DD, Friedman HS, Rich JN. Shi Q, et al. Among authors: hjelmeland ab. Mol Carcinog. 2007 Jun;46(6):488-96. doi: 10.1002/mc.20297. Mol Carcinog. 2007. PMID: 17219439

10

The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion.

Hjelmeland AB, Lattimore KP, Fee BE, Shi Q, Wickman S, Keir ST, Hjelmeland MD, Batt D, Bigner DD, Friedman HS, Rich JN. Hjelmeland AB, et al. Among authors: hjelmeland md. Mol Cancer Ther. 2007 Sep;6(9):2449-57. doi: 10.1158/1535-7163.MCT-07-0155. Epub 2007 Aug 31. Mol Cancer Ther. 2007. PMID: 17766837

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