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Long-term cytomegalovirus infection leads to significant changes in the composition of the CD8+ T-cell repertoire, which may be the basis for an imbalance in the cytokine production profile in elderly persons.
Almanzar G, Schwaiger S, Jenewein B, Keller M, Herndler-Brandstetter D, Würzner R, Schönitzer D, Grubeck-Loebenstein B. Almanzar G, et al. J Virol. 2005 Mar;79(6):3675-83. doi: 10.1128/JVI.79.6.3675-3683.2005. J Virol. 2005. PMID: 15731261 Free PMC article.
CD25-expressing CD8+ T cells are potent memory cells in old age.
Herndler-Brandstetter D, Schwaiger S, Veel E, Fehrer C, Cioca DP, Almanzar G, Keller M, Pfister G, Parson W, Würzner R, Schönitzer D, Henson SM, Aspinall R, Lepperdinger G, Grubeck-Loebenstein B. Herndler-Brandstetter D, et al. J Immunol. 2005 Aug 1;175(3):1566-74. doi: 10.4049/jimmunol.175.3.1566. J Immunol. 2005. PMID: 16034095
Biology of immune responses to vaccines in elderly persons.
Weinberger B, Herndler-Brandstetter D, Schwanninger A, Weiskopf D, Grubeck-Loebenstein B. Weinberger B, et al. Clin Infect Dis. 2008 Apr 1;46(7):1078-84. doi: 10.1086/529197. Clin Infect Dis. 2008. PMID: 18444828 Review.
Persistent viral infections and immune aging.
Brunner S, Herndler-Brandstetter D, Weinberger B, Grubeck-Loebenstein B. Brunner S, et al. Ageing Res Rev. 2011 Jul;10(3):362-9. doi: 10.1016/j.arr.2010.08.003. Epub 2010 Aug 19. Ageing Res Rev. 2011. PMID: 20727987 Review.
47 results