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Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.
Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T. Watanabe T, et al. J Biol Chem. 2009 Jan 16;284(3):1803-12. doi: 10.1074/jbc.M807120200. Epub 2008 Nov 13. J Biol Chem. 2009. PMID: 19008231 Free article.
Overexpression of monocyte chemoattractant protein-1 in adipose tissues causes macrophage recruitment and insulin resistance.
Kamei N, Tobe K, Suzuki R, Ohsugi M, Watanabe T, Kubota N, Ohtsuka-Kowatari N, Kumagai K, Sakamoto K, Kobayashi M, Yamauchi T, Ueki K, Oishi Y, Nishimura S, Manabe I, Hashimoto H, Ohnishi Y, Ogata H, Tokuyama K, Tsunoda M, Ide T, Murakami K, Nagai R, Kadowaki T. Kamei N, et al. Among authors: watanabe t. J Biol Chem. 2006 Sep 8;281(36):26602-14. doi: 10.1074/jbc.M601284200. Epub 2006 Jun 29. J Biol Chem. 2006. PMID: 16809344 Free article.
[Insulin resistance in central nerve system].
Watanabe T, Tobe K, Kadowaki T, Kamei N. Watanabe T, et al. Nihon Rinsho. 2006 Dec 28;64 Suppl 9:158-62. Nihon Rinsho. 2006. PMID: 17458211 Review. Japanese. No abstract available.
Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.
Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, Inoue M, Takamoto I, Sasako T, Kumagai K, Kohjima M, Nakamuta M, Moroi M, Sugi K, Noda T, Terauchi Y, Ueki K, Kadowaki T. Kubota N, et al. Among authors: watanabe t. Nat Commun. 2016 Oct 6;7:12977. doi: 10.1038/ncomms12977. Nat Commun. 2016. PMID: 27708333 Free PMC article.
Homeostatic and pathogenic roles of GM3 ganglioside molecular species in TLR4 signaling in obesity.
Kanoh H, Nitta T, Go S, Inamori KI, Veillon L, Nihei W, Fujii M, Kabayama K, Shimoyama A, Fukase K, Ohto U, Shimizu T, Watanabe T, Shindo H, Aoki S, Sato K, Nagasaki M, Yatomi Y, Komura N, Ando H, Ishida H, Kiso M, Natori Y, Yoshimura Y, Zonca A, Cattaneo A, Letizia M, Ciampa M, Mauri L, Prinetti A, Sonnino S, Suzuki A, Inokuchi JI. Kanoh H, et al. Among authors: watanabe t. EMBO J. 2020 Jun 17;39(12):e101732. doi: 10.15252/embj.2019101732. Epub 2020 May 7. EMBO J. 2020. PMID: 32378734 Free PMC article.
Immune evasion through mitochondrial transfer in the tumour microenvironment.
Ikeda H, Kawase K, Nishi T, Watanabe T, Takenaga K, Inozume T, Ishino T, Aki S, Lin J, Kawashima S, Nagasaki J, Ueda Y, Suzuki S, Makinoshima H, Itami M, Nakamura Y, Tatsumi Y, Suenaga Y, Morinaga T, Honobe-Tabuchi A, Ohnuma T, Kawamura T, Umeda Y, Nakamura Y, Kiniwa Y, Ichihara E, Hayashi H, Ikeda JI, Hanazawa T, Toyooka S, Mano H, Suzuki T, Osawa T, Kawazu M, Togashi Y. Ikeda H, et al. Among authors: watanabe t. Nature. 2025 Jan 22. doi: 10.1038/s41586-024-08439-0. Online ahead of print. Nature. 2025. PMID: 39843734
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