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Metabolic activation of benzodiazepines by CYP3A4.
Mizuno K, Katoh M, Okumura H, Nakagawa N, Negishi T, Hashizume T, Nakajima M, Yokoi T. Mizuno K, et al. Among authors: nakajima m. Drug Metab Dispos. 2009 Feb;37(2):345-51. doi: 10.1124/dmd.108.024521. Epub 2008 Nov 12. Drug Metab Dispos. 2009. PMID: 19005028
Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.
Yamazaki H, Nakamura M, Komatsu T, Ohyama K, Hatanaka N, Asahi S, Shimada N, Guengerich FP, Shimada T, Nakajima M, Yokoi T. Yamazaki H, et al. Among authors: nakajima m. Protein Expr Purif. 2002 Apr;24(3):329-37. doi: 10.1006/prep.2001.1578. Protein Expr Purif. 2002. PMID: 11922748
Evaluation of approach to predict the contribution of multiple cytochrome P450s in drug metabolism using relative activity factor: effects of the differences in expression levels of NADPH-cytochrome P450 reductase and cytochrome b(5) in the expression system and the differences in the marker activities.
Nakajima M, Tane K, Nakamura S, Shimada N, Yamazaki H, Yokoi T. Nakajima M, et al. J Pharm Sci. 2002 Apr;91(4):952-63. doi: 10.1002/jps.10091. J Pharm Sci. 2002. PMID: 11948533
3,755 results