Mizuno K - Search Results

1

Metabolic activation of benzodiazepines by CYP3A4.

Mizuno K, Katoh M, Okumura H, Nakagawa N, Negishi T, Hashizume T, Nakajima M, Yokoi T. Mizuno K, et al. Drug Metab Dispos. 2009 Feb;37(2):345-51. doi: 10.1124/dmd.108.024521. Epub 2008 Nov 12. Drug Metab Dispos. 2009. PMID: 19005028

2

Interleukin-17 is involved in alpha-naphthylisothiocyanate-induced liver injury in mice.

Kobayashi M, Higuchi S, Mizuno K, Tsuneyama K, Fukami T, Nakajima M, Yokoi T. Kobayashi M, et al. Among authors: mizuno k. Toxicology. 2010 Sep 10;275(1-3):50-7. doi: 10.1016/j.tox.2010.05.011. Epub 2010 Jun 8. Toxicology. 2010. PMID: 20594950

3

Terbinafine stimulates the pro-inflammatory responses in human monocytic THP-1 cells through an ERK signaling pathway.

Mizuno K, Fukami T, Toyoda Y, Nakajima M, Yokoi T. Mizuno K, et al. Life Sci. 2010 Oct 23;87(17-18):537-44. doi: 10.1016/j.lfs.2010.08.010. Epub 2010 Sep 9. Life Sci. 2010. PMID: 20816994

4

Stimulation of pro-inflammatory responses by mebendazole in human monocytic THP-1 cells through an ERK signaling pathway.

Mizuno K, Toyoda Y, Fukami T, Nakajima M, Yokoi T. Mizuno K, et al. Arch Toxicol. 2011 Mar;85(3):199-207. doi: 10.1007/s00204-010-0584-y. Epub 2010 Sep 17. Arch Toxicol. 2011. PMID: 20848085

5

Establishment of MDCKII cell monolayer with metabolic activity by CYP3A4 transduced with recombinant adenovirus.

Kataoka M, Terashima Y, Mizuno K, Masaoka Y, Sakuma S, Yokoi T, Yamashita S. Kataoka M, et al. Among authors: mizuno k. Drug Metab Pharmacokinet. 2013;28(2):125-31. doi: 10.2133/dmpk.dmpk-12-rg-059. Epub 2012 Aug 14. Drug Metab Pharmacokinet. 2013. PMID: 22892444 Free article.

6

Identification of a novel metabolite of vildagliptin in humans: Cysteine targets the nitrile moiety to form a thiazoline ring.

Mizuno K, Takeuchi K, Umehara K, Nakajima M. Mizuno K, et al. Biochem Pharmacol. 2018 Oct;156:312-321. doi: 10.1016/j.bcp.2018.08.043. Epub 2018 Aug 31. Biochem Pharmacol. 2018. PMID: 30172711

7

Identification of Novel Metabolites of Vildagliptin in Rats: Thiazoline-Containing Thiol Adducts Formed via Cysteine or Glutathione Conjugation.

Mizuno K, Takeuchi K, Umehara K, Nakajima M. Mizuno K, et al. Drug Metab Dispos. 2019 Aug;47(8):809-817. doi: 10.1124/dmd.119.086546. Epub 2019 May 16. Drug Metab Dispos. 2019. PMID: 31097424

8

Altered Hepatobiliary Disposition of Tolvaptan and Selected Tolvaptan Metabolites in a Rodent Model of Polycystic Kidney Disease.

Beaudoin JJ, Bezençon J, Cao Y, Mizuno K, Roth SE, Brock WJ, Brouwer KLR. Beaudoin JJ, et al. Among authors: mizuno k. Drug Metab Dispos. 2019 Feb;47(2):155-163. doi: 10.1124/dmd.118.083907. Epub 2018 Nov 30. Drug Metab Dispos. 2019. PMID: 30504136 Free PMC article.

9

Delamanid does not inhibit or induce cytochrome p450 enzymes in vitro.

Shimokawa Y, Sasahara K, Yoda N, Mizuno K, Umehara K. Shimokawa Y, et al. Among authors: mizuno k. Biol Pharm Bull. 2014;37(11):1727-35. doi: 10.1248/bpb.b14-00311. Biol Pharm Bull. 2014. PMID: 25366478 Free article.

10

Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy.

Saito S, Yamamoto Y, Maki T, Hattori Y, Ito H, Mizuno K, Harada-Shiba M, Kalaria RN, Fukushima M, Takahashi R, Ihara M. Saito S, et al. Among authors: mizuno k. Acta Neuropathol Commun. 2017 Apr 4;5(1):26. doi: 10.1186/s40478-017-0429-5. Acta Neuropathol Commun. 2017. PMID: 28376923 Free PMC article.

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