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Page 1
Preclinical studies of celastrol and acetyl isogambogic acid in melanoma.
Abbas S, Bhoumik A, Dahl R, Vasile S, Krajewski S, Cosford ND, Ronai ZA. Abbas S, et al. Among authors: cosford nd. Clin Cancer Res. 2007 Nov 15;13(22 Pt 1):6769-78. doi: 10.1158/1078-0432.CCR-07-1536. Clin Cancer Res. 2007. PMID: 18006779 Free PMC article.
Design, synthesis and evaluation of monovalent Smac mimetics that bind to the BIR2 domain of the anti-apoptotic protein XIAP.
González-López M, Welsh K, Finlay D, Ardecky RJ, Ganji SR, Su Y, Yuan H, Teriete P, Mace PD, Riedl SJ, Vuori K, Reed JC, Cosford ND. González-López M, et al. Among authors: cosford nd. Bioorg Med Chem Lett. 2011 Jul 15;21(14):4332-6. doi: 10.1016/j.bmcl.2011.05.049. Epub 2011 May 24. Bioorg Med Chem Lett. 2011. PMID: 21680182 Free PMC article.
Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation.
Sergienko E, Xu J, Liu WH, Dahl R, Critton DA, Su Y, Brown BT, Chan X, Yang L, Bobkova EV, Vasile S, Yuan H, Rascon J, Colayco S, Sidique S, Cosford ND, Chung TD, Mustelin T, Page R, Lombroso PJ, Tautz L. Sergienko E, et al. Among authors: cosford nd. ACS Chem Biol. 2012 Feb 17;7(2):367-77. doi: 10.1021/cb2004274. Epub 2011 Nov 17. ACS Chem Biol. 2012. PMID: 22070201 Free PMC article.
Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.
Ardecky RJ, Welsh K, Finlay D, Lee PS, González-López M, Ganji SR, Ravanan P, Mace PD, Riedl SJ, Vuori K, Reed JC, Cosford ND. Ardecky RJ, et al. Among authors: cosford nd. Bioorg Med Chem Lett. 2013 Jul 15;23(14):4253-7. doi: 10.1016/j.bmcl.2013.04.096. Epub 2013 May 14. Bioorg Med Chem Lett. 2013. PMID: 23743278 Free PMC article.
103 results