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Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis.
Nielsen R, Pedersen TA, Hagenbeek D, Moulos P, Siersbaek R, Megens E, Denissov S, Børgesen M, Francoijs KJ, Mandrup S, Stunnenberg HG. Nielsen R, et al. Among authors: mandrup s. Genes Dev. 2008 Nov 1;22(21):2953-67. doi: 10.1101/gad.501108. Genes Dev. 2008. PMID: 18981474 Free PMC article.
The gene encoding the Acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor gamma through an intronic response element functionally conserved between humans and rodents.
Helledie T, Grøntved L, Jensen SS, Kiilerich P, Rietveld L, Albrektsen T, Boysen MS, Nøhr J, Larsen LK, Fleckner J, Stunnenberg HG, Kristiansen K, Mandrup S. Helledie T, et al. Among authors: mandrup s. J Biol Chem. 2002 Jul 26;277(30):26821-30. doi: 10.1074/jbc.M111295200. Epub 2002 May 15. J Biol Chem. 2002. PMID: 12015306 Free article.
ACBP--a PPAR and SREBP modulated housekeeping gene.
Neess D, Kiilerich P, Sandberg MB, Helledie T, Nielsen R, Mandrup S. Neess D, et al. Among authors: mandrup s. Mol Cell Biochem. 2006 Mar;284(1-2):149-57. doi: 10.1007/s11010-005-9039-9. Epub 2006 Jan 13. Mol Cell Biochem. 2006. PMID: 16411019
Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver.
Lalloyer F, Pedersen TA, Gross B, Lestavel S, Yous S, Vallez E, Gustafsson JA, Mandrup S, Fiévet C, Staels B, Tailleux A. Lalloyer F, et al. Among authors: mandrup s. Arterioscler Thromb Vasc Biol. 2009 Oct;29(10):1488-95. doi: 10.1161/ATVBAHA.109.189506. Epub 2009 Jul 10. Arterioscler Thromb Vasc Biol. 2009. PMID: 19592467 Free PMC article.
158 results