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Dipeptidyl peptidase-4 inhibition prevents nonalcoholic steatohepatitis-associated liver fibrosis and tumor development in mice independently of its anti-diabetic effects.
Kawakubo M, Tanaka M, Ochi K, Watanabe A, Saka-Tanaka M, Kanamori Y, Yoshioka N, Yamashita S, Goto M, Itoh M, Shirakawa I, Kanai S, Suzuki H, Sawada M, Ito A, Ishigami M, Fujishiro M, Arima H, Ogawa Y, Suganami T. Kawakubo M, et al. Among authors: ito a. Sci Rep. 2020 Jan 22;10(1):983. doi: 10.1038/s41598-020-57935-6. Sci Rep. 2020. PMID: 31969650 Free PMC article.
C-type lectin Mincle mediates cell death-triggered inflammation in acute kidney injury.
Tanaka M, Saka-Tanaka M, Ochi K, Fujieda K, Sugiura Y, Miyamoto T, Kohda H, Ito A, Miyazawa T, Matsumoto A, Aoe S, Miyamoto Y, Tsuboi N, Maruyama S, Suematsu M, Yamasaki S, Ogawa Y, Suganami T. Tanaka M, et al. Among authors: ito a. J Exp Med. 2020 Nov 2;217(11):e20192230. doi: 10.1084/jem.20192230. J Exp Med. 2020. PMID: 32797195 Free PMC article.
The sodium-glucose cotransporter-2 inhibitor Tofogliflozin prevents the progression of nonalcoholic steatohepatitis-associated liver tumors in a novel murine model.
Yoshioka N, Tanaka M, Ochi K, Watanabe A, Ono K, Sawada M, Ogi T, Itoh M, Ito A, Shiraki Y, Enomoto A, Ishigami M, Fujishiro M, Ogawa Y, Suganami T. Yoshioka N, et al. Among authors: ito a. Biomed Pharmacother. 2021 Aug;140:111738. doi: 10.1016/j.biopha.2021.111738. Epub 2021 May 21. Biomed Pharmacother. 2021. PMID: 34029949 Free article.
Lysosomal cholesterol overload in macrophages promotes liver fibrosis in a mouse model of NASH.
Itoh M, Tamura A, Kanai S, Tanaka M, Kanamori Y, Shirakawa I, Ito A, Oka Y, Hidaka I, Takami T, Honda Y, Maeda M, Saito Y, Murata Y, Matozaki T, Nakajima A, Kataoka Y, Ogi T, Ogawa Y, Suganami T. Itoh M, et al. Among authors: ito a. J Exp Med. 2023 Nov 6;220(11):e20220681. doi: 10.1084/jem.20220681. Epub 2023 Sep 19. J Exp Med. 2023. PMID: 37725372 Free PMC article.
4,438 results