Topalis D - Search Results

1

Crystal structure of poxvirus thymidylate kinase: an unexpected dimerization has implications for antiviral therapy.

Caillat C, Topalis D, Agrofoglio LA, Pochet S, Balzarini J, Deville-Bonne D, Meyer P. Caillat C, et al. Among authors: topalis d. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):16900-5. doi: 10.1073/pnas.0804525105. Epub 2008 Oct 29. Proc Natl Acad Sci U S A. 2008. PMID: 18971333 Free PMC article.

2

Substrate specificity of vaccinia virus thymidylate kinase.

Topalis D, Collinet B, Gasse C, Dugué L, Balzarini J, Pochet S, Deville-Bonne D. Topalis D, et al. FEBS J. 2005 Dec;272(24):6254-65. doi: 10.1111/j.1742-4658.2005.05006.x. FEBS J. 2005. PMID: 16336263 Free article.

3

Structural basis for the specificity of thymidylate kinases from human pathogens: implications for nucleotide analogues activation.

Meyer P, Caillat C, Topalis D, Balzarini J, Deville-Bonne D. Meyer P, et al. Among authors: topalis d. Nucleic Acids Symp Ser (Oxf). 2009;(53):41. doi: 10.1093/nass/nrp021. Nucleic Acids Symp Ser (Oxf). 2009. PMID: 19749250

4

Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.

Topalis D, Pradère U, Roy V, Caillat C, Azzouzi A, Broggi J, Snoeck R, Andrei G, Lin J, Eriksson S, Alexandre JA, El-Amri C, Deville-Bonne D, Meyer P, Balzarini J, Agrofoglio LA. Topalis D, et al. J Med Chem. 2011 Jan 13;54(1):222-32. doi: 10.1021/jm1011462. Epub 2010 Dec 3. J Med Chem. 2011. PMID: 21128666

5

Nucleotide binding to human UMP-CMP kinase using fluorescent derivatives -- a screening based on affinity for the UMP-CMP binding site.

Topalis D, Kumamoto H, Amaya Velasco MF, Dugué L, Haouz A, Alexandre JAC, Gallois-Montbrun S, Alzari PM, Pochet S, Agrofoglio LA, Deville-Bonne D. Topalis D, et al. FEBS J. 2007 Jul;274(14):3704-3714. doi: 10.1111/j.1742-4658.2007.05902.x. Epub 2007 Jul 2. FEBS J. 2007. PMID: 17608725 Free article.

6

Enantioselectivity of human AMP, dTMP and UMP-CMP kinases.

Alexandre JA, Roy B, Topalis D, Pochet S, Périgaud C, Deville-Bonne D. Alexandre JA, et al. Among authors: topalis d. Nucleic Acids Res. 2007;35(14):4895-904. doi: 10.1093/nar/gkm479. Epub 2007 Jul 10. Nucleic Acids Res. 2007. PMID: 17626051 Free PMC article.

7

Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human UMP-CMP kinase.

Topalis D, Kumamoto H, Alexandre JA, Dugué L, Pochet S, Berteina-Raboin S, Agrofoglio LA, Deville-Bonne D. Topalis D, et al. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1369-73. doi: 10.1080/15257770701533982. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066785

8

Phosphorylation of dGMP analogs by vaccinia virus TMP kinase and human GMP kinase.

Auvynet C, Topalis D, Caillat C, Munier-Lehmann H, Seclaman E, Balzarini J, Agrofoglio LA, Kaminski PA, Meyer P, Deville-Bonne D, El Amri C. Auvynet C, et al. Among authors: topalis d. Biochem Biophys Res Commun. 2009 Oct 9;388(1):6-11. doi: 10.1016/j.bbrc.2009.07.089. Epub 2009 Jul 23. Biochem Biophys Res Commun. 2009. PMID: 19631609

9

Enantio-selectivity of human nucleoside monophosphate kinases.

Alexandre JA, Roy B, Topalis D, Périgaud C, Deville-Bonne D. Alexandre JA, et al. Among authors: topalis d. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1375-9. doi: 10.1080/15257770701534014. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18066786

10

Acyclic phosphonate nucleotides and human adenylate kinases: impact of a borano group on alpha-P position.

Topalis D, Alvarez K, Barral K, Munier-Lehmann H, Schneider B, Véron M, Guerreiro C, Mulard L, El-Amri C, Canard B, Deville-Bonne D. Topalis D, et al. Nucleosides Nucleotides Nucleic Acids. 2008 Apr;27(4):319-31. doi: 10.1080/15257770801941952. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18404568

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