Kieffer TJ - Search Results

1

Transplantation of PC1/3-Expressing alpha-cells improves glucose handling and cold tolerance in leptin-resistant mice.

Wideman RD, Gray SL, Covey SD, Webb GC, Kieffer TJ. Wideman RD, et al. Among authors: kieffer tj. Mol Ther. 2009 Jan;17(1):191-8. doi: 10.1038/mt.2008.219. Epub 2008 Oct 21. Mol Ther. 2009. PMID: 18941442 Free PMC article.

2

Leptin reduces glucose transport and cellular ATP levels in INS-1 beta-cells.

Lam NT, Cheung AT, Riedel MJ, Light PE, Cheeseman CI, Kieffer TJ. Lam NT, et al. Among authors: kieffer tj. J Mol Endocrinol. 2004 Apr;32(2):415-24. doi: 10.1677/jme.0.0320415. J Mol Endocrinol. 2004. PMID: 15072548

3

Glucose-dependent insulinotropic polypeptide as a regulator of beta cell function and fate.

Wideman RD, Kieffer TJ. Wideman RD, et al. Among authors: kieffer tj. Horm Metab Res. 2004 Nov-Dec;36(11-12):782-6. doi: 10.1055/s-2004-826164. Horm Metab Res. 2004. PMID: 15655709 Review.

4

Leptin resistance following over-expression of protein tyrosine phosphatase 1B in liver.

Lam NT, Covey SD, Lewis JT, Oosman S, Webber T, Hsu EC, Cheung AT, Kieffer TJ. Lam NT, et al. Among authors: kieffer tj. J Mol Endocrinol. 2006 Feb;36(1):163-74. doi: 10.1677/jme.1.01937. J Mol Endocrinol. 2006. PMID: 16461936

5

Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1).

Wideman RD, Yu IL, Webber TD, Verchere CB, Johnson JD, Cheung AT, Kieffer TJ. Wideman RD, et al. Among authors: kieffer tj. Proc Natl Acad Sci U S A. 2006 Sep 5;103(36):13468-73. doi: 10.1073/pnas.0600655103. Epub 2006 Aug 28. Proc Natl Acad Sci U S A. 2006. PMID: 16938896 Free PMC article.

6

The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.

Covey SD, Wideman RD, McDonald C, Unniappan S, Huynh F, Asadi A, Speck M, Webber T, Chua SC, Kieffer TJ. Covey SD, et al. Among authors: kieffer tj. Cell Metab. 2006 Oct;4(4):291-302. doi: 10.1016/j.cmet.2006.09.005. Cell Metab. 2006. PMID: 17011502 Free article.

7

A switch from prohormone convertase (PC)-2 to PC1/3 expression in transplanted alpha-cells is accompanied by differential processing of proglucagon and improved glucose homeostasis in mice.

Wideman RD, Covey SD, Webb GC, Drucker DJ, Kieffer TJ. Wideman RD, et al. Among authors: kieffer tj. Diabetes. 2007 Nov;56(11):2744-52. doi: 10.2337/db07-0563. Epub 2007 Aug 13. Diabetes. 2007. PMID: 17698597

8

Treatment of obesity and diabetes in mice by transplant of gut cells engineered to produce leptin.

Oosman SN, Lam AW, Harb G, Unniappan S, Lam NT, Webber T, Bruch D, Zhang QX, Korbutt GS, Kieffer TJ. Oosman SN, et al. Among authors: kieffer tj. Mol Ther. 2008 Jun;16(6):1138-45. doi: 10.1038/mt.2008.62. Epub 2008 Apr 15. Mol Ther. 2008. PMID: 18414479 Free article.

9

Pax6 and Pdx1 are required for production of glucose-dependent insulinotropic polypeptide in proglucagon-expressing L cells.

Fujita Y, Chui JW, King DS, Zhang T, Seufert J, Pownall S, Cheung AT, Kieffer TJ. Fujita Y, et al. Among authors: kieffer tj. Am J Physiol Endocrinol Metab. 2008 Sep;295(3):E648-57. doi: 10.1152/ajpendo.90440.2008. Epub 2008 Jul 1. Am J Physiol Endocrinol Metab. 2008. PMID: 18593849 Free article.

10

Incretin release from gut is acutely enhanced by sugar but not by sweeteners in vivo.

Fujita Y, Wideman RD, Speck M, Asadi A, King DS, Webber TD, Haneda M, Kieffer TJ. Fujita Y, et al. Among authors: kieffer tj. Am J Physiol Endocrinol Metab. 2009 Mar;296(3):E473-9. doi: 10.1152/ajpendo.90636.2008. Epub 2008 Dec 23. Am J Physiol Endocrinol Metab. 2009. PMID: 19106249 Free article.

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