Liang Y - Search Results

1

Improvement of dyslipidemia, insulin sensitivity, and energy balance by a peroxisome proliferator-activated receptor alpha agonist.

Chen X, Matthews J, Zhou L, Pelton P, Liang Y, Xu J, Yang M, Cryan E, Rybczynski P, Demarest K. Chen X, et al. Among authors: liang y. Metabolism. 2008 Nov;57(11):1516-25. doi: 10.1016/j.metabol.2008.06.005. Metabolism. 2008. PMID: 18940388

2

The messenger RNA profiles in liver, hypothalamus, white adipose tissue, and skeletal muscle of female Zucker diabetic fatty rats after topiramate treatment.

Liang Y, She P, Wang X, Demarest K. Liang Y, et al. Metabolism. 2006 Oct;55(10):1411-9. doi: 10.1016/j.metabol.2006.06.013. Metabolism. 2006. PMID: 16979414

3

Antisense oligonucleotides targeted against glucocorticoid receptor reduce hepatic glucose production and ameliorate hyperglycemia in diabetic mice.

Liang Y, Osborne MC, Monia BP, Bhanot S, Watts LM, She P, DeCarlo SO, Chen X, Demarest K. Liang Y, et al. Metabolism. 2005 Jul;54(7):848-55. doi: 10.1016/j.metabol.2005.01.030. Metabolism. 2005. PMID: 15988691

4

Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice.

Liang Y, Osborne MC, Monia BP, Bhanot S, Gaarde WA, Reed C, She P, Jetton TL, Demarest KT. Liang Y, et al. Diabetes. 2004 Feb;53(2):410-7. doi: 10.2337/diabetes.53.2.410. Diabetes. 2004. PMID: 14747292

5

Synthesis and biological evaluation of 3-aryl-3-(4-phenoxy)-propionic acid as a novel series of G protein-coupled receptor 40 agonists.

Song F, Lu S, Gunnet J, Xu JZ, Wines P, Proost J, Liang Y, Baumann C, Lenhard J, Murray WV, Demarest KT, Kuo GH. Song F, et al. Among authors: liang y. J Med Chem. 2007 Jun 14;50(12):2807-17. doi: 10.1021/jm070130j. Epub 2007 May 15. J Med Chem. 2007. PMID: 17500511

6

Beneficial metabolic effects of CB1R anti-sense oligonucleotide treatment in diet-induced obese AKR/J mice.

Tang Y, Ho G, Li Y, Hall MA, Hills RL, Black SC, Liang Y, Demarest KT. Tang Y, et al. Among authors: liang y. PLoS One. 2012;7(8):e42134. doi: 10.1371/journal.pone.0042134. Epub 2012 Aug 3. PLoS One. 2012. PMID: 22870290 Free PMC article.

7

Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.

Dudash J Jr, Zhang Y, Moore JB, Look R, Liang Y, Beavers MP, Conway BR, Rybczynski PJ, Demarest KT. Dudash J Jr, et al. Among authors: liang y. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4790-3. doi: 10.1016/j.bmcl.2005.07.021. Bioorg Med Chem Lett. 2005. PMID: 16143521

8

Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models.

Liang Y, Arakawa K, Ueta K, Matsushita Y, Kuriyama C, Martin T, Du F, Liu Y, Xu J, Conway B, Conway J, Polidori D, Ways K, Demarest K. Liang Y, et al. PLoS One. 2012;7(2):e30555. doi: 10.1371/journal.pone.0030555. Epub 2012 Feb 15. PLoS One. 2012. PMID: 22355316 Free PMC article.

9

Evaluation of anti-diabetic effect and gall bladder function with 2-thio-5-thiomethyl substituted imidazoles as TGR5 receptor agonists.

Zhang X, Sui Z, Kauffman J, Hou C, Chen C, Du F, Kirchner T, Liang Y, Johnson D, Murray WV, Demarest K. Zhang X, et al. Among authors: liang y. Bioorg Med Chem Lett. 2017 Apr 15;27(8):1760-1764. doi: 10.1016/j.bmcl.2017.02.069. Epub 2017 Feb 28. Bioorg Med Chem Lett. 2017. PMID: 28285911

10

5,5-Difluoro- and 5-Fluoro-5-methyl-hexose-based C-Glucosides as potent and orally bioavailable SGLT1 and SGLT2 dual inhibitors.

Xu G, Du F, Kuo GH, Xu JZ, Liang Y, Demarest K, Gaul MD. Xu G, et al. Among authors: liang y. Bioorg Med Chem Lett. 2020 Sep 1;30(17):127387. doi: 10.1016/j.bmcl.2020.127387. Epub 2020 Jul 5. Bioorg Med Chem Lett. 2020. PMID: 32738984

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