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Page 1
Inactivation of effector caspases through nondegradative polyubiquitylation.
Ditzel M, Broemer M, Tenev T, Bolduc C, Lee TV, Rigbolt KT, Elliott R, Zvelebil M, Blagoev B, Bergmann A, Meier P. Ditzel M, et al. Among authors: zvelebil m. Mol Cell. 2008 Nov 21;32(4):540-53. doi: 10.1016/j.molcel.2008.09.025. Mol Cell. 2008. PMID: 19026784 Free PMC article.
MoKCa database--mutations of kinases in cancer.
Richardson CJ, Gao Q, Mitsopoulous C, Zvelebil M, Pearl LH, Pearl FM. Richardson CJ, et al. Among authors: zvelebil m. Nucleic Acids Res. 2009 Jan;37(Database issue):D824-31. doi: 10.1093/nar/gkn832. Epub 2008 Nov 5. Nucleic Acids Res. 2009. PMID: 18986996 Free PMC article.
PPM1D is a potential therapeutic target in ovarian clear cell carcinomas.
Tan DS, Lambros MB, Rayter S, Natrajan R, Vatcheva R, Gao Q, Marchiò C, Geyer FC, Savage K, Parry S, Fenwick K, Tamber N, Mackay A, Dexter T, Jameson C, McCluggage WG, Williams A, Graham A, Faratian D, El-Bahrawy M, Paige AJ, Gabra H, Gore ME, Zvelebil M, Lord CJ, Kaye SB, Ashworth A, Reis-Filho JS. Tan DS, et al. Among authors: zvelebil m. Clin Cancer Res. 2009 Apr 1;15(7):2269-80. doi: 10.1158/1078-0432.CCR-08-2403. Epub 2009 Mar 17. Clin Cancer Res. 2009. PMID: 19293255
Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention.
Bohnacker T, Prota AE, Beaufils F, Burke JE, Melone A, Inglis AJ, Rageot D, Sele AM, Cmiljanovic V, Cmiljanovic N, Bargsten K, Aher A, Akhmanova A, Díaz JF, Fabbro D, Zvelebil M, Williams RL, Steinmetz MO, Wymann MP. Bohnacker T, et al. Among authors: zvelebil m. Nat Commun. 2017 Mar 9;8:14683. doi: 10.1038/ncomms14683. Nat Commun. 2017. PMID: 28276440 Free PMC article.
Comprehensive genomic analysis of a BRCA2 deficient human pancreatic cancer.
Barber LJ, Rosa Rosa JM, Kozarewa I, Fenwick K, Assiotis I, Mitsopoulos C, Sims D, Hakas J, Zvelebil M, Lord CJ, Ashworth A. Barber LJ, et al. Among authors: zvelebil m. PLoS One. 2011;6(7):e21639. doi: 10.1371/journal.pone.0021639. Epub 2011 Jul 5. PLoS One. 2011. PMID: 21750719 Free PMC article.
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk.
Orr N, Lemnrau A, Cooke R, Fletcher O, Tomczyk K, Jones M, Johnson N, Lord CJ, Mitsopoulos C, Zvelebil M, McDade SS, Buck G, Blancher C; KConFab Consortium; Trainer AH, James PA, Bojesen SE, Bokmand S, Nevanlinna H, Mattson J, Friedman E, Laitman Y, Palli D, Masala G, Zanna I, Ottini L, Giannini G, Hollestelle A, Ouweland AM, Novaković S, Krajc M, Gago-Dominguez M, Castelao JE, Olsson H, Hedenfalk I, Easton DF, Pharoah PD, Dunning AM, Bishop DT, Neuhausen SL, Steele L, Houlston RS, Garcia-Closas M, Ashworth A, Swerdlow AJ. Orr N, et al. Among authors: zvelebil m. Nat Genet. 2012 Nov;44(11):1182-4. doi: 10.1038/ng.2417. Epub 2012 Sep 23. Nat Genet. 2012. PMID: 23001122 Free PMC article.
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