Barnes MH - Search Results

1

An essential DnaB helicase of Bacillus anthracis: identification, characterization, and mechanism of action.

Biswas EE, Barnes MH, Moir DT, Biswas SB. Biswas EE, et al. Among authors: barnes mh. J Bacteriol. 2009 Jan;191(1):249-60. doi: 10.1128/JB.01259-08. Epub 2008 Oct 17. J Bacteriol. 2009. PMID: 18931108 Free PMC article.

2

Discovery, characterization and comparison of inhibitors of Bacillus anthracis and Staphylococcus aureus replicative DNA helicases.

Aiello D, Barnes MH, Biswas EE, Biswas SB, Gu S, Williams JD, Bowlin TL, Moir DT. Aiello D, et al. Among authors: barnes mh. Bioorg Med Chem. 2009 Jul 1;17(13):4466-76. doi: 10.1016/j.bmc.2009.05.014. Epub 2009 May 12. Bioorg Med Chem. 2009. PMID: 19477652 Free PMC article.

3

Coumarin-based inhibitors of Bacillus anthracis and Staphylococcus aureus replicative DNA helicase: chemical optimization, biological evaluation, and antibacterial activities.

Li B, Pai R, Di M, Aiello D, Barnes MH, Butler MM, Tashjian TF, Peet NP, Bowlin TL, Moir DT. Li B, et al. Among authors: barnes mh. J Med Chem. 2012 Dec 27;55(24):10896-908. doi: 10.1021/jm300922h. Epub 2012 Dec 11. J Med Chem. 2012. PMID: 23231076 Free PMC article.

4

Optimization of a novel potent and selective bacterial DNA helicase inhibitor scaffold from a high throughput screening hit.

Li B, Pai R, Aiello D, Di M, Barnes MH, Peet NP, Bowlin TL, Moir DT. Li B, et al. Among authors: barnes mh. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3481-6. doi: 10.1016/j.bmcl.2013.04.055. Epub 2013 Apr 30. Bioorg Med Chem Lett. 2013. PMID: 23664213 Free PMC article.

5

DNA polymerases of low-GC gram-positive eubacteria: identification of the replication-specific enzyme encoded by dnaE.

Barnes MH, Miller SD, Brown NC. Barnes MH, et al. J Bacteriol. 2002 Jul;184(14):3834-8. doi: 10.1128/JB.184.14.3834-3838.2002. J Bacteriol. 2002. PMID: 12081953 Free PMC article.

6

Cloning and characterization of the polC region of Bacillus subtilis.

Ott RW, Barnes MH, Brown NC, Ganesan AT. Ott RW, et al. Among authors: barnes mh. J Bacteriol. 1986 Mar;165(3):951-7. doi: 10.1128/jb.165.3.951-957.1986. J Bacteriol. 1986. PMID: 2936731 Free PMC article.

7

The 3'-5' exonuclease site of DNA polymerase III from gram-positive bacteria: definition of a novel motif structure.

Barnes MH, Spacciapoli P, Li DH, Brown NC. Barnes MH, et al. Gene. 1995 Nov 7;165(1):45-50. doi: 10.1016/0378-1119(95)00530-j. Gene. 1995. PMID: 7489914

8

Antimicrobials targeted to the replication-specific DNA polymerases of gram-positive bacteria: target potential of dnaE.

Barnes MH, Butler MM, Wright GE, Brown NC. Barnes MH, et al. Infect Disord Drug Targets. 2012 Oct;12(5):327-31. doi: 10.2174/187152612804142279. Infect Disord Drug Targets. 2012. PMID: 23017159

9

Bacillus subtilis DNA polymerase III: complete sequence, overexpression, and characterization of the polC gene.

Hammond RA, Barnes MH, Mack SL, Mitchener JA, Brown NC. Hammond RA, et al. Among authors: barnes mh. Gene. 1991 Feb 1;98(1):29-36. doi: 10.1016/0378-1119(91)90100-p. Gene. 1991. PMID: 1901559

10

DNA polymerase III of Gram-positive eubacteria is a zinc metalloprotein conserving an essential finger-like domain.

Barnes MH, Leo CJ, Brown NC. Barnes MH, et al. Biochemistry. 1998 Nov 3;37(44):15254-60. doi: 10.1021/bi981113m. Biochemistry. 1998. PMID: 9799485

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