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Activation of a HIF1alpha-PPARgamma axis underlies the integration of glycolytic and lipid anabolic pathways in pathologic cardiac hypertrophy.
Krishnan J, Suter M, Windak R, Krebs T, Felley A, Montessuit C, Tokarska-Schlattner M, Aasum E, Bogdanova A, Perriard E, Perriard JC, Larsen T, Pedrazzini T, Krek W. Krishnan J, et al. Among authors: krek w. Cell Metab. 2009 Jun;9(6):512-24. doi: 10.1016/j.cmet.2009.05.005. Cell Metab. 2009. PMID: 19490906 Free article.
Inhibition of the Hypoxia-Inducible Factor 1α-Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease.
Mirtschink P, Bischof C, Pham MD, Sharma R, Khadayate S, Rossi G, Fankhauser N, Traub S, Sossalla S, Hagag E, Berthonneche C, Sarre A, Stehr SN, Grote P, Pedrazzini T, Dimmeler S, Krek W, Krishnan J. Mirtschink P, et al. Among authors: krek w. Circulation. 2019 Jun 11;139(24):2778-2792. doi: 10.1161/CIRCULATIONAHA.118.036769. Epub 2019 Mar 29. Circulation. 2019. PMID: 30922078 Free PMC article.
HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease.
Mirtschink P, Krishnan J, Grimm F, Sarre A, Hörl M, Kayikci M, Fankhauser N, Christinat Y, Cortijo C, Feehan O, Vukolic A, Sossalla S, Stehr SN, Ule J, Zamboni N, Pedrazzini T, Krek W. Mirtschink P, et al. Among authors: krek w. Nature. 2015 Jun 25;522(7557):444-449. doi: 10.1038/nature14508. Epub 2015 Jun 17. Nature. 2015. PMID: 26083752 Free PMC article.
The hypoxia-inducible microRNA cluster miR-199a∼214 targets myocardial PPARδ and impairs mitochondrial fatty acid oxidation.
el Azzouzi H, Leptidis S, Dirkx E, Hoeks J, van Bree B, Brand K, McClellan EA, Poels E, Sluimer JC, van den Hoogenhof MM, Armand AS, Yin X, Langley S, Bourajjaj M, Olieslagers S, Krishnan J, Vooijs M, Kurihara H, Stubbs A, Pinto YM, Krek W, Mayr M, da Costa Martins PA, Schrauwen P, De Windt LJ. el Azzouzi H, et al. Among authors: krek w. Cell Metab. 2013 Sep 3;18(3):341-54. doi: 10.1016/j.cmet.2013.08.009. Cell Metab. 2013. PMID: 24011070 Free article.
Multitasking by pVHL in tumour suppression.
Frew IJ, Krek W. Frew IJ, et al. Among authors: krek w. Curr Opin Cell Biol. 2007 Dec;19(6):685-90. doi: 10.1016/j.ceb.2007.10.001. Epub 2007 Nov 19. Curr Opin Cell Biol. 2007. PMID: 18006292 Review.
109 results