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Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype.
Fuentes L, Wouters K, Hannou SA, Cudejko C, Rigamonti E, Mayi TH, Derudas B, Pattou F, Chinetti-Gbaguidi G, Staels B, Paumelle R. Fuentes L, et al. Among authors: paumelle r. Diabetologia. 2011 Dec;54(12):3150-6. doi: 10.1007/s00125-011-2324-0. Epub 2011 Oct 4. Diabetologia. 2011. PMID: 21968977 Free PMC article.
Endoplasmic reticulum stress actively suppresses hepatic molecular identity in damaged liver.
Dubois V, Gheeraert C, Vankrunkelsven W, Dubois-Chevalier J, Dehondt H, Bobowski-Gerard M, Vinod M, Zummo FP, Güiza F, Ploton M, Dorchies E, Pineau L, Boulinguiez A, Vallez E, Woitrain E, Baugé E, Lalloyer F, Duhem C, Rabhi N, van Kesteren RE, Chiang CM, Lancel S, Duez H, Annicotte JS, Paumelle R, Vanhorebeek I, Van den Berghe G, Staels B, Lefebvre P, Eeckhoute J. Dubois V, et al. Among authors: paumelle r. Mol Syst Biol. 2020 May;16(5):e9156. doi: 10.15252/msb.20199156. Mol Syst Biol. 2020. PMID: 32407006 Free PMC article.
p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages.
Cudejko C, Wouters K, Fuentes L, Hannou SA, Paquet C, Bantubungi K, Bouchaert E, Vanhoutte J, Fleury S, Remy P, Tailleux A, Chinetti-Gbaguidi G, Dombrowicz D, Staels B, Paumelle R. Cudejko C, et al. Among authors: paumelle r. Blood. 2011 Sep 1;118(9):2556-66. doi: 10.1182/blood-2010-10-313106. Epub 2011 Jun 2. Blood. 2011. PMID: 21636855 Free PMC article.
Chromatin recruitment of activated AMPK drives fasting response genes co-controlled by GR and PPARα.
Ratman D, Mylka V, Bougarne N, Pawlak M, Caron S, Hennuyer N, Paumelle R, De Cauwer L, Thommis J, Rider MH, Libert C, Lievens S, Tavernier J, Staels B, De Bosscher K. Ratman D, et al. Among authors: paumelle r. Nucleic Acids Res. 2016 Dec 15;44(22):10539-10553. doi: 10.1093/nar/gkw742. Epub 2016 Aug 30. Nucleic Acids Res. 2016. PMID: 27576532 Free PMC article.
37 results