Anderson AC - Search Results

1

Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from cryptosporidium.

Bolstad DB, Bolstad ES, Frey KM, Wright DL, Anderson AC. Bolstad DB, et al. Among authors: anderson ac. J Med Chem. 2008 Nov 13;51(21):6839-52. doi: 10.1021/jm8009124. Epub 2008 Oct 4. J Med Chem. 2008. PMID: 18834108 Free PMC article.

2

Structure-based approach to pharmacophore identification, in silico screening, and three-dimensional quantitative structure-activity relationship studies for inhibitors of Trypanosoma cruzi dihydrofolate reductase function.

Schormann N, Senkovich O, Walker K, Wright DL, Anderson AC, Rosowsky A, Ananthan S, Shinkre B, Velu S, Chattopadhyay D. Schormann N, et al. Among authors: anderson ac. Proteins. 2008 Dec;73(4):889-901. doi: 10.1002/prot.22115. Proteins. 2008. PMID: 18536013

3

Highly efficient ligands for dihydrofolate reductase from Cryptosporidium hominis and Toxoplasma gondii inspired by structural analysis.

Pelphrey PM, Popov VM, Joska TM, Beierlein JM, Bolstad ES, Fillingham YA, Wright DL, Anderson AC. Pelphrey PM, et al. Among authors: anderson ac. J Med Chem. 2007 Mar 8;50(5):940-50. doi: 10.1021/jm061027h. Epub 2007 Feb 2. J Med Chem. 2007. PMID: 17269758

4

In pursuit of virtual lead optimization: the role of the receptor structure and ensembles in accurate docking.

Bolstad ES, Anderson AC. Bolstad ES, et al. Among authors: anderson ac. Proteins. 2008 Nov 15;73(3):566-80. doi: 10.1002/prot.22081. Proteins. 2008. PMID: 18473360 Free PMC article.

5

In pursuit of virtual lead optimization: pruning ensembles of receptor structures for increased efficiency and accuracy during docking.

Bolstad ES, Anderson AC. Bolstad ES, et al. Among authors: anderson ac. Proteins. 2009 Apr;75(1):62-74. doi: 10.1002/prot.22214. Proteins. 2009. PMID: 18781587 Free PMC article.

6

Structure-guided development of efficacious antifungal agents targeting Candida glabrata dihydrofolate reductase.

Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC. Liu J, et al. Among authors: anderson ac. Chem Biol. 2008 Sep 22;15(9):990-6. doi: 10.1016/j.chembiol.2008.07.013. Chem Biol. 2008. PMID: 18804036 Free PMC article.

7

Synthetic and crystallographic studies of a new inhibitor series targeting Bacillus anthracis dihydrofolate reductase.

Beierlein JM, Frey KM, Bolstad DB, Pelphrey PM, Joska TM, Smith AE, Priestley ND, Wright DL, Anderson AC. Beierlein JM, et al. Among authors: anderson ac. J Med Chem. 2008 Dec 11;51(23):7532-40. doi: 10.1021/jm800776a. J Med Chem. 2008. PMID: 19007108 Free PMC article.

8

Probing the active site of Candida glabrata dihydrofolate reductase with high resolution crystal structures and the synthesis of new inhibitors.

Liu J, Bolstad DB, Smith AE, Priestley ND, Wright DL, Anderson AC. Liu J, et al. Among authors: anderson ac. Chem Biol Drug Des. 2009 Jan;73(1):62-74. doi: 10.1111/j.1747-0285.2008.00745.x. Chem Biol Drug Des. 2009. PMID: 19152636 Free PMC article.

9

Towards new antifolates targeting eukaryotic opportunistic infections.

Liu J, Bolstad DB, Bolstad ES, Wright DL, Anderson AC. Liu J, et al. Among authors: anderson ac. Eukaryot Cell. 2009 Apr;8(4):483-6. doi: 10.1128/EC.00298-08. Epub 2009 Jan 23. Eukaryot Cell. 2009. PMID: 19168759 Free PMC article.

10

Inhibitors of phosphoinositide-3-kinase: a structure-based approach to understanding potency and selectivity.

Sundstrom TJ, Anderson AC, Wright DL. Sundstrom TJ, et al. Among authors: anderson ac. Org Biomol Chem. 2009 Mar 7;7(5):840-50. doi: 10.1039/b819067b. Epub 2009 Jan 8. Org Biomol Chem. 2009. PMID: 19225663 Review.

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