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Stroke by inducing HDAC9-dependent deacetylation of HIF-1 and Sp1, promotes TfR1 transcription and GPX4 reduction, thus determining ferroptotic neuronal death.
Sanguigno L, Guida N, Anzilotti S, Cuomo O, Mascolo L, Serani A, Brancaccio P, Pennacchio G, Licastro E, Pignataro G, Molinaro P, Annunziato L, Formisano L. Sanguigno L, et al. Among authors: mascolo l. Int J Biol Sci. 2023 May 11;19(9):2695-2710. doi: 10.7150/ijbs.80735. eCollection 2023. Int J Biol Sci. 2023. PMID: 37324938 Free PMC article.
Use of a non-specific immunomodulation therapy as a therapeutic vasculogenesis strategy in no-option critical limb ischemia patients.
Marfella R, Luongo C, Coppola A, Luongo M, Capodanno P, Ruggiero R, Mascolo L, Ambrosino I, Sardu C, Boccardi V, Lettieri B, Paolisso G. Marfella R, et al. Among authors: mascolo l. Atherosclerosis. 2010 Feb;208(2):473-9. doi: 10.1016/j.atherosclerosis.2009.08.005. Epub 2009 Aug 8. Atherosclerosis. 2010. PMID: 19709658 Clinical Trial.
Daily Oxygen/O₃ Treatment Reduces Muscular Fatigue and Improves Cardiac Performance in Rats Subjected to Prolonged High Intensity Physical Exercise.
Di Filippo C, Trotta MC, Maisto R, Siniscalco D, Luongo M, Mascolo L, Alfano R, Accardo M, Rossi C, Ferraraccio F, D'Amico M. Di Filippo C, et al. Among authors: mascolo l. Oxid Med Cell Longev. 2015;2015:190640. doi: 10.1155/2015/190640. Epub 2015 Jul 21. Oxid Med Cell Longev. 2015. PMID: 26265981 Free PMC article.
HDAC4 and HDAC5 form a complex with DREAM that epigenetically down-regulates NCX3 gene and its pharmacological inhibition reduces neuronal stroke damage.
Formisano L, Laudati G, Guida N, Mascolo L, Serani A, Cuomo O, Cantile M, Boscia F, Molinaro P, Anzilotti S, Pizzorusso V, Di Renzo G, Pignataro G, Annunziato L. Formisano L, et al. Among authors: mascolo l. J Cereb Blood Flow Metab. 2020 Oct;40(10):2081-2097. doi: 10.1177/0271678X19884742. Epub 2019 Nov 7. J Cereb Blood Flow Metab. 2020. PMID: 31696766 Free PMC article.
32 results