Dantuma NP - Search Results

1

Functional alterations of the ubiquitin-proteasome system in motor neurons of a mouse model of familial amyotrophic lateral sclerosis.

Cheroni C, Marino M, Tortarolo M, Veglianese P, De Biasi S, Fontana E, Zuccarello LV, Maynard CJ, Dantuma NP, Bendotti C. Cheroni C, et al. Among authors: dantuma np. Hum Mol Genet. 2009 Jan 1;18(1):82-96. doi: 10.1093/hmg/ddn319. Epub 2008 Sep 29. Hum Mol Genet. 2009. PMID: 18826962 Free PMC article.

2

Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation.

Bowman AB, Yoo SY, Dantuma NP, Zoghbi HY. Bowman AB, et al. Among authors: dantuma np. Hum Mol Genet. 2005 Mar 1;14(5):679-91. doi: 10.1093/hmg/ddi064. Epub 2005 Jan 20. Hum Mol Genet. 2005. PMID: 15661755

3

Endoplasmic reticulum stress compromises the ubiquitin-proteasome system.

Menéndez-Benito V, Verhoef LG, Masucci MG, Dantuma NP. Menéndez-Benito V, et al. Among authors: dantuma np. Hum Mol Genet. 2005 Oct 1;14(19):2787-99. doi: 10.1093/hmg/ddi312. Epub 2005 Aug 15. Hum Mol Genet. 2005. PMID: 16103128

4

A fluorescent broad-spectrum proteasome inhibitor for labeling proteasomes in vitro and in vivo.

Verdoes M, Florea BI, Menendez-Benito V, Maynard CJ, Witte MD, van der Linden WA, van den Nieuwendijk AM, Hofmann T, Berkers CR, van Leeuwen FW, Groothuis TA, Leeuwenburgh MA, Ovaa H, Neefjes JJ, Filippov DV, van der Marel GA, Dantuma NP, Overkleeft HS. Verdoes M, et al. Among authors: dantuma np. Chem Biol. 2006 Nov;13(11):1217-26. doi: 10.1016/j.chembiol.2006.09.013. Chem Biol. 2006. PMID: 17114003

5

Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment.

Maynard CJ, Böttcher C, Ortega Z, Smith R, Florea BI, Díaz-Hernández M, Brundin P, Overkleeft HS, Li JY, Lucas JJ, Dantuma NP. Maynard CJ, et al. Among authors: dantuma np. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13986-91. doi: 10.1073/pnas.0906463106. Epub 2009 Jul 30. Proc Natl Acad Sci U S A. 2009. PMID: 19666572 Free PMC article.

6

Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation.

Ortega Z, Díaz-Hernández M, Maynard CJ, Hernández F, Dantuma NP, Lucas JJ. Ortega Z, et al. Among authors: dantuma np. J Neurosci. 2010 Mar 10;30(10):3675-88. doi: 10.1523/JNEUROSCI.5673-09.2010. J Neurosci. 2010. PMID: 20220001 Free PMC article.

7

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation.

Viswanathan J, Haapasalo A, Böttcher C, Miettinen R, Kurkinen KM, Lu A, Thomas A, Maynard CJ, Romano D, Hyman BT, Berezovska O, Bertram L, Soininen H, Dantuma NP, Tanzi RE, Hiltunen M. Viswanathan J, et al. Among authors: dantuma np. Traffic. 2011 Mar;12(3):330-48. doi: 10.1111/j.1600-0854.2010.01149.x. Epub 2011 Jan 7. Traffic. 2011. PMID: 21143716 Free PMC article.

8

Aggregate formation inhibits proteasomal degradation of polyglutamine proteins.

Verhoef LG, Lindsten K, Masucci MG, Dantuma NP. Verhoef LG, et al. Among authors: dantuma np. Hum Mol Genet. 2002 Oct 15;11(22):2689-700. doi: 10.1093/hmg/11.22.2689. Hum Mol Genet. 2002. PMID: 12374759

9

A transgenic mouse model of the ubiquitin/proteasome system.

Lindsten K, Menéndez-Benito V, Masucci MG, Dantuma NP. Lindsten K, et al. Among authors: dantuma np. Nat Biotechnol. 2003 Aug;21(8):897-902. doi: 10.1038/nbt851. Epub 2003 Jul 20. Nat Biotechnol. 2003. PMID: 12872133

10

Monitoring the ubiquitin/proteasome system in conformational diseases.

Lindsten K, Dantuma NP. Lindsten K, et al. Among authors: dantuma np. Ageing Res Rev. 2003 Oct;2(4):433-49. doi: 10.1016/s1568-1637(03)00031-x. Ageing Res Rev. 2003. PMID: 14522245 Review.

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