Hirano K - Search Results

1

Delta-like 4 is indispensable in thymic environment specific for T cell development.

Hozumi K, Mailhos C, Negishi N, Hirano K, Yahata T, Ando K, Zuklys S, Holländer GA, Shima DT, Habu S. Hozumi K, et al. Among authors: hirano k. J Exp Med. 2008 Oct 27;205(11):2507-13. doi: 10.1084/jem.20080134. Epub 2008 Sep 29. J Exp Med. 2008. PMID: 18824583 Free PMC article.

2

Notch signaling is necessary for GATA3 function in the initiation of T cell development.

Hozumi K, Negishi N, Tsuchiya I, Abe N, Hirano K, Suzuki D, Yamamoto M, Engel JD, Habu S. Hozumi K, et al. Among authors: hirano k. Eur J Immunol. 2008 Apr;38(4):977-85. doi: 10.1002/eji.200737688. Eur J Immunol. 2008. PMID: 18383037 Free article.

3

Notch ligands transduce different magnitudes of signaling critical for determination of T-cell fate.

Abe N, Hozumi K, Hirano K, Yagita H, Habu S. Abe N, et al. Among authors: hirano k. Eur J Immunol. 2010 Sep;40(9):2608-17. doi: 10.1002/eji.200940006. Eur J Immunol. 2010. PMID: 20602435 Free article.

4

Delta-like 4-mediated Notch signaling is required for early T-cell development in a three-dimensional thymic structure.

Hirano K, Negishi N, Yazawa M, Yagita H, Habu S, Hozumi K. Hirano K, et al. Eur J Immunol. 2015 Aug;45(8):2252-62. doi: 10.1002/eji.201445123. Epub 2015 Jun 3. Eur J Immunol. 2015. PMID: 25976373 Free article.

5

Anti-fibrotic effects of a novel small compound on the regulation of cytokine production in a mouse model of colorectal fibrosis.

Imai J, Hozumi K, Sumiyoshi H, Yazawa M, Hirano K, Abe J, Higashi K, Inagaki Y, Mine T. Imai J, et al. Among authors: hirano k. Biochem Biophys Res Commun. 2015 Dec 25;468(4):554-60. doi: 10.1016/j.bbrc.2015.10.123. Epub 2015 Nov 19. Biochem Biophys Res Commun. 2015. PMID: 26603932

6

Peripheral PDGFRα⁺gp38⁺ mesenchymal cells support the differentiation of fetal liver-derived ILC2.

Koga S, Hozumi K, Hirano KI, Yazawa M, Terooatea T, Minoda A, Nagasawa T, Koyasu S, Moro K. Koga S, et al. Among authors: hirano ki. J Exp Med. 2018 Jun 4;215(6):1609-1626. doi: 10.1084/jem.20172310. Epub 2018 May 4. J Exp Med. 2018. PMID: 29728440 Free PMC article.

7

Delta-like 1 and Delta-like 4 differently require their extracellular domains for triggering Notch signaling in mice.

Hirano KI, Suganami A, Tamura Y, Yagita H, Habu S, Kitagawa M, Sato T, Hozumi K. Hirano KI, et al. Elife. 2020 Jan 16;9:e50979. doi: 10.7554/eLife.50979. Elife. 2020. PMID: 31934853 Free PMC article.

8

Targeting of plasminogen activator inhibitor-1 activity promotes elimination of chronic myeloid leukemia stem cells.

Yahata T, Ibrahim AA, Hirano KI, Muguruma Y, Naka K, Hozumi K, Vaughan DE, Miyata T, Ando K. Yahata T, et al. Among authors: hirano ki. Haematologica. 2021 Feb 1;106(2):483-494. doi: 10.3324/haematol.2019.230227. Haematologica. 2021. PMID: 32001531 Free PMC article.

9

Notch signaling supports the appearance of follicular helper T cells in the Peyer's patches concomitantly with the reduction of regulatory T cells.

Yazawa M, Hosokawa H, Koizumi M, Hirano KI, Imai J, Hozumi K. Yazawa M, et al. Among authors: hirano ki. Int Immunol. 2021 Aug 23;33(9):469-478. doi: 10.1093/intimm/dxab032. Int Immunol. 2021. PMID: 34147033

10

LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice.

Hirano KI, Hosokawa H, Koizumi M, Endo Y, Yahata T, Ando K, Hozumi K. Hirano KI, et al. Elife. 2021 Aug 12;10:e68227. doi: 10.7554/eLife.68227. Elife. 2021. PMID: 34382935 Free PMC article.

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