Gewirtz AM - Search Results

1

The c-myb proto-oncogene and microRNA-15a comprise an active autoregulatory feedback loop in human hematopoietic cells.

Zhao H, Kalota A, Jin S, Gewirtz AM. Zhao H, et al. Among authors: gewirtz am. Blood. 2009 Jan 15;113(3):505-16. doi: 10.1182/blood-2008-01-136218. Epub 2008 Sep 25. Blood. 2009. PMID: 18818396 Free PMC article.

2

Neuromedin U: a Myb-regulated autocrine growth factor for human myeloid leukemias.

Shetzline SE, Rallapalli R, Dowd KJ, Zou S, Nakata Y, Swider CR, Kalota A, Choi JK, Gewirtz AM. Shetzline SE, et al. Among authors: gewirtz am. Blood. 2004 Sep 15;104(6):1833-40. doi: 10.1182/blood-2003-10-3577. Epub 2004 Jun 8. Blood. 2004. PMID: 15187020 Free article.

3

c-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression.

Nakata Y, Shetzline S, Sakashita C, Kalota A, Rallapalli R, Rudnick SI, Zhang Y, Emerson SG, Gewirtz AM. Nakata Y, et al. Among authors: gewirtz am. Mol Cell Biol. 2007 Mar;27(6):2048-58. doi: 10.1128/MCB.01100-06. Epub 2007 Jan 22. Mol Cell Biol. 2007. PMID: 17242210 Free PMC article.

4

Trisomy 21 enhances human fetal erythro-megakaryocytic development.

Chou ST, Opalinska JB, Yao Y, Fernandes MA, Kalota A, Brooks JS, Choi JK, Gewirtz AM, Danet-Desnoyers GA, Nemiroff RL, Weiss MJ. Chou ST, et al. Among authors: gewirtz am. Blood. 2008 Dec 1;112(12):4503-6. doi: 10.1182/blood-2008-05-157859. Epub 2008 Sep 23. Blood. 2008. PMID: 18812473 Free PMC article.

5

A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells.

Kalota A, Gewirtz AM. Kalota A, et al. Among authors: gewirtz am. Blood. 2010 Jan 7;115(1):89-93. doi: 10.1182/blood-2009-06-227751. Epub 2009 Oct 30. Blood. 2010. PMID: 19880492 Free article.

6

c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.

Jin S, Zhao H, Yi Y, Nakata Y, Kalota A, Gewirtz AM. Jin S, et al. Among authors: gewirtz am. J Clin Invest. 2010 Feb;120(2):593-606. doi: 10.1172/JCI38030. Epub 2010 Jan 19. J Clin Invest. 2010. PMID: 20093773 Free PMC article.

7

c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development.

Nakata Y, Brignier AC, Jin S, Shen Y, Rudnick SI, Sugita M, Gewirtz AM. Nakata Y, et al. Among authors: gewirtz am. Blood. 2010 Aug 26;116(8):1280-90. doi: 10.1182/blood-2009-05-223255. Epub 2010 May 18. Blood. 2010. PMID: 20484083 Free PMC article.

8

The histone acetyltransferase TIP60 interacts with c-Myb and inactivates its transcriptional activity in human leukemia.

Zhao H, Jin S, Gewirtz AM. Zhao H, et al. Among authors: gewirtz am. J Biol Chem. 2012 Jan 6;287(2):925-34. doi: 10.1074/jbc.M111.279950. Epub 2011 Nov 21. J Biol Chem. 2012. PMID: 22110127 Free PMC article.

9

The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.

Clappier E, Cuccuini W, Kalota A, Crinquette A, Cayuela JM, Dik WA, Langerak AW, Montpellier B, Nadel B, Walrafen P, Delattre O, Aurias A, Leblanc T, Dombret H, Gewirtz AM, Baruchel A, Sigaux F, Soulier J. Clappier E, et al. Among authors: gewirtz am. Blood. 2007 Aug 15;110(4):1251-61. doi: 10.1182/blood-2006-12-064683. Epub 2007 Apr 23. Blood. 2007. PMID: 17452517 Free article.

10

Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules.

Opalinska JB, Kalota A, Gifford LK, Lu P, Jen KY, Pradeepkumar PI, Barman J, Kim TK, Swider CR, Chattopadhyaya J, Gewirtz AM. Opalinska JB, et al. Among authors: gewirtz am. Nucleic Acids Res. 2004 Oct 28;32(19):5791-9. doi: 10.1093/nar/gkh893. Print 2004. Nucleic Acids Res. 2004. PMID: 15514112 Free PMC article.

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