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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions.
Tomasini R, Tsuchihara K, Wilhelm M, Fujitani M, Rufini A, Cheung CC, Khan F, Itie-Youten A, Wakeham A, Tsao MS, Iovanna JL, Squire J, Jurisica I, Kaplan D, Melino G, Jurisicova A, Mak TW. Tomasini R, et al. Among authors: tsuchihara k. Genes Dev. 2008 Oct 1;22(19):2677-91. doi: 10.1101/gad.1695308. Epub 2008 Sep 19. Genes Dev. 2008. PMID: 18805989 Free PMC article.
TAp73 regulates the spindle assembly checkpoint by modulating BubR1 activity.
Tomasini R, Tsuchihara K, Tsuda C, Lau SK, Wilhelm M, Rufini A, Tsao MS, Iovanna JL, Jurisicova A, Melino G, Mak TW. Tomasini R, et al. Among authors: tsuchihara k. Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):797-802. doi: 10.1073/pnas.0812096106. Epub 2009 Jan 12. Proc Natl Acad Sci U S A. 2009. PMID: 19139399 Free PMC article.
Carnitine palmitoyltransferase 1C promotes cell survival and tumor growth under conditions of metabolic stress.
Zaugg K, Yao Y, Reilly PT, Kannan K, Kiarash R, Mason J, Huang P, Sawyer SK, Fuerth B, Faubert B, Kalliomäki T, Elia A, Luo X, Nadeem V, Bungard D, Yalavarthi S, Growney JD, Wakeham A, Moolani Y, Silvester J, Ten AY, Bakker W, Tsuchihara K, Berger SL, Hill RP, Jones RG, Tsao M, Robinson MO, Thompson CB, Pan G, Mak TW. Zaugg K, et al. Among authors: tsuchihara k. Genes Dev. 2011 May 15;25(10):1041-51. doi: 10.1101/gad.1987211. Genes Dev. 2011. PMID: 21576264 Free PMC article.
Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model.
Sanchez-Macedo N, Feng J, Faubert B, Chang N, Elia A, Rushing EJ, Tsuchihara K, Bungard D, Berger SL, Jones RG, Mak TW, Zaugg K. Sanchez-Macedo N, et al. Among authors: tsuchihara k. Cell Death Differ. 2013 Apr;20(4):659-68. doi: 10.1038/cdd.2012.168. Epub 2013 Feb 15. Cell Death Differ. 2013. PMID: 23412344 Free PMC article.
189 results