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Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma.
Perales MA, Yuan J, Powel S, Gallardo HF, Rasalan TS, Gonzalez C, Manukian G, Wang J, Zhang Y, Chapman PB, Krown SE, Livingston PO, Ejadi S, Panageas KS, Engelhorn ME, Terzulli SL, Houghton AN, Wolchok JD. Perales MA, et al. Mol Ther. 2008 Dec;16(12):2022-9. doi: 10.1038/mt.2008.196. Epub 2008 Sep 16. Mol Ther. 2008. PMID: 18797450 Free PMC article. Clinical Trial.
Strategies to overcome immune ignorance and tolerance.
Perales MA, Blachere NE, Engelhorn ME, Ferrone CR, Gold JS, Gregor PD, Noffz G, Wolchok JD, Houghton AN. Perales MA, et al. Semin Cancer Biol. 2002 Feb;12(1):63-71. doi: 10.1006/scbi.2001.0397. Semin Cancer Biol. 2002. PMID: 11926414 Review.
Melanoma vaccines.
Perales MA, Wolchok JD. Perales MA, et al. Cancer Invest. 2002;20(7-8):1012-26. doi: 10.1081/cnv-120005918. Cancer Invest. 2002. PMID: 12449735 Review.
CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems.
Gregor PD, Wolchok JD, Ferrone CR, Buchinshky H, Guevara-Patiño JA, Perales MA, Mortazavi F, Bacich D, Heston W, Latouche JB, Sadelain M, Allison JP, Scher HI, Houghton AN. Gregor PD, et al. Among authors: perales ma. Vaccine. 2004 Apr 16;22(13-14):1700-8. doi: 10.1016/j.vaccine.2003.10.048. Vaccine. 2004. PMID: 15068853
443 results