Rubin EH - Search Results

1

Pharmacokinetic/pharmacodynamic modeling and simulation of neutropenia during phase I development of liposome-entrapped paclitaxel.

Fetterly GJ, Grasela TH, Sherman JW, Dul JL, Grahn A, Lecomte D, Fiedler-Kelly J, Damjanov N, Fishman M, Kane MP, Rubin EH, Tan AR. Fetterly GJ, et al. Among authors: rubin eh. Clin Cancer Res. 2008 Sep 15;14(18):5856-63. doi: 10.1158/1078-0432.CCR-08-1046. Clin Cancer Res. 2008. PMID: 18794097 Clinical Trial.

2

Pharmacokinetics of cetuximab after administration of escalating single dosing and weekly fixed dosing in patients with solid tumors.

Tan AR, Moore DF, Hidalgo M, Doroshow JH, Poplin EA, Goodin S, Mauro D, Rubin EH. Tan AR, et al. Among authors: rubin eh. Clin Cancer Res. 2006 Nov 1;12(21):6517-22. doi: 10.1158/1078-0432.CCR-06-0705. Epub 2006 Oct 25. Clin Cancer Res. 2006. PMID: 17065274 Clinical Trial.

3

Phase I study of eribulin mesylate administered once every 21 days in patients with advanced solid tumors.

Tan AR, Rubin EH, Walton DC, Shuster DE, Wong YN, Fang F, Ashworth S, Rosen LS. Tan AR, et al. Among authors: rubin eh. Clin Cancer Res. 2009 Jun 15;15(12):4213-9. doi: 10.1158/1078-0432.CCR-09-0360. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509146 Clinical Trial.

4

Rationally designed treatment for solid tumors with MAPK pathway activation: a phase I study of paclitaxel and bortezomib using an adaptive dose-finding approach.

Mehnert JM, Tan AR, Moss R, Poplin E, Stein MN, Sovak M, Levinson K, Lin H, Kane M, Gounder M, Lin Y, Shih WJ, White E, Rubin EH, Karantza V. Mehnert JM, et al. Among authors: rubin eh. Mol Cancer Ther. 2011 Aug;10(8):1509-19. doi: 10.1158/1535-7163.MCT-10-0944. Epub 2011 Jun 16. Mol Cancer Ther. 2011. PMID: 21680752 Free PMC article. Clinical Trial.

5

A phase 1 trial of E7974 administered on day 1 of a 21-day cycle in patients with advanced solid tumors.

Rocha-Lima CM, Bayraktar S, Macintyre J, Raez L, Flores AM, Ferrell A, Rubin EH, Poplin EA, Tan AR, Lucarelli A, Zojwalla N. Rocha-Lima CM, et al. Among authors: rubin eh. Cancer. 2012 Sep 1;118(17):4262-70. doi: 10.1002/cncr.27428. Epub 2012 Jan 31. Cancer. 2012. PMID: 22294459 Free article. Clinical Trial.

6

A phase I trial of a potent P-glycoprotein inhibitor, Zosuquidar.3HCl trihydrochloride (LY335979), administered orally in combination with doxorubicin in patients with advanced malignancies.

Rubin EH, de Alwis DP, Pouliquen I, Green L, Marder P, Lin Y, Musanti R, Grospe SL, Smith SL, Toppmeyer DL, Much J, Kane M, Chaudhary A, Jordan C, Burgess M, Slapak CA. Rubin EH, et al. Clin Cancer Res. 2002 Dec;8(12):3710-7. Clin Cancer Res. 2002. PMID: 12473580 Clinical Trial.

7

Epothilones: mechanism of action and biologic activity.

Goodin S, Kane MP, Rubin EH. Goodin S, et al. Among authors: rubin eh. J Clin Oncol. 2004 May 15;22(10):2015-25. doi: 10.1200/JCO.2004.12.001. J Clin Oncol. 2004. PMID: 15143095 Review.

8

Phase I and pharmacokinetic study of imatinib mesylate (Gleevec) and gemcitabine in patients with refractory solid tumors.

Ali Y, Lin Y, Gharibo MM, Gounder MK, Stein MN, Lagattuta TF, Egorin MJ, Rubin EH, Poplin EA. Ali Y, et al. Among authors: rubin eh. Clin Cancer Res. 2007 Oct 1;13(19):5876-82. doi: 10.1158/1078-0432.CCR-07-0883. Clin Cancer Res. 2007. PMID: 17908982 Clinical Trial.

9

A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin.

Rubin E, Wood V, Bharti A, Trites D, Lynch C, Hurwitz S, Bartel S, Levy S, Rosowsky A, Toppmeyer D, et al. Rubin E, et al. Clin Cancer Res. 1995 Mar;1(3):269-76. Clin Cancer Res. 1995. PMID: 9815982 Clinical Trial.

10

Phase I evaluation of sequential topoisomerase targeting with irinotecan/cisplatin followed by etoposide in patients with advanced malignancy.

Licitra EJ, Vyas V, Nelson K, Musanti R, Beers S, Thomas C, Poplin E, Smith S, Lin Y, Schaaf LJ, Aisner J, Gounder M, Rajendra R, Saleem A, Toppmeyer D, Rubin EH. Licitra EJ, et al. Among authors: rubin eh. Clin Cancer Res. 2003 May;9(5):1673-9. Clin Cancer Res. 2003. PMID: 12738720 Clinical Trial.

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