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LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein.
Yamada M, Toba S, Yoshida Y, Haratani K, Mori D, Yano Y, Mimori-Kiyosue Y, Nakamura T, Itoh K, Fushiki S, Setou M, Wynshaw-Boris A, Torisawa T, Toyoshima YY, Hirotsune S. Yamada M, et al. Among authors: toyoshima yy. EMBO J. 2008 Oct 8;27(19):2471-83. doi: 10.1038/emboj.2008.182. Epub 2008 Sep 11. EMBO J. 2008. PMID: 18784752 Free PMC article.
Recruitment of katanin p60 by phosphorylated NDEL1, an LIS1 interacting protein, is essential for mitotic cell division and neuronal migration.
Toyo-Oka K, Sasaki S, Yano Y, Mori D, Kobayashi T, Toyoshima YY, Tokuoka SM, Ishii S, Shimizu T, Muramatsu M, Hiraiwa N, Yoshiki A, Wynshaw-Boris A, Hirotsune S. Toyo-Oka K, et al. Among authors: toyoshima yy. Hum Mol Genet. 2005 Nov 1;14(21):3113-28. doi: 10.1093/hmg/ddi339. Epub 2005 Oct 3. Hum Mol Genet. 2005. PMID: 16203747
CRMP-2 directly binds to cytoplasmic dynein and interferes with its activity.
Arimura N, Hattori A, Kimura T, Nakamuta S, Funahashi Y, Hirotsune S, Furuta K, Urano T, Toyoshima YY, Kaibuchi K. Arimura N, et al. Among authors: toyoshima yy. J Neurochem. 2009 Oct;111(2):380-90. doi: 10.1111/j.1471-4159.2009.06317.x. Epub 2009 Jul 31. J Neurochem. 2009. PMID: 19659462 Free article.
Dynein and kinesin share an overlapping microtubule-binding site.
Mizuno N, Toba S, Edamatsu M, Watai-Nishii J, Hirokawa N, Toyoshima YY, Kikkawa M. Mizuno N, et al. Among authors: toyoshima yy. EMBO J. 2004 Jul 7;23(13):2459-67. doi: 10.1038/sj.emboj.7600240. Epub 2004 Jun 3. EMBO J. 2004. PMID: 15175652 Free PMC article.
75 results