Funahashi Y - Search Results

1

Multi-kinase inhibitor E7080 suppresses lymph node and lung metastases of human mammary breast tumor MDA-MB-231 via inhibition of vascular endothelial growth factor-receptor (VEGF-R) 2 and VEGF-R3 kinase.

Matsui J, Funahashi Y, Uenaka T, Watanabe T, Tsuruoka A, Asada M. Matsui J, et al. Among authors: funahashi y. Clin Cancer Res. 2008 Sep 1;14(17):5459-65. doi: 10.1158/1078-0432.CCR-07-5270. Clin Cancer Res. 2008. PMID: 18765537

2

In vivo tumor growth inhibition produced by a novel sulfonamide, E7010, against rodent and human tumors.

Koyanagi N, Nagasu T, Fujita F, Watanabe T, Tsukahara K, Funahashi Y, Fujita M, Taguchi T, Yoshino H, Kitoh K. Koyanagi N, et al. Among authors: funahashi y. Cancer Res. 1994 Apr 1;54(7):1702-6. Cancer Res. 1994. PMID: 8137285

3

Establishment of a quantitative mouse dorsal air sac model and its application to evaluate a new angiogenesis inhibitor.

Funahashi Y, Wakabayashi T, Semba T, Sonoda J, Kitoh K, Yoshimatsu K. Funahashi Y, et al. Oncol Res. 1999;11(7):319-29. Oncol Res. 1999. PMID: 10757446

4

Sulfonamide derivative, E7820, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium.

Funahashi Y, Sugi NH, Semba T, Yamamoto Y, Hamaoka S, Tsukahara-Tamai N, Ozawa Y, Tsuruoka A, Nara K, Takahashi K, Okabe T, Kamata J, Owa T, Ueda N, Haneda T, Yonaga M, Yoshimatsu K, Wakabayashi T. Funahashi Y, et al. Cancer Res. 2002 Nov 1;62(21):6116-23. Cancer Res. 2002. PMID: 12414636

5

An angiogenesis inhibitor E7820 shows broad-spectrum tumor growth inhibition in a xenograft model: possible value of integrin alpha2 on platelets as a biological marker.

Semba T, Funahashi Y, Ono N, Yamamoto Y, Sugi NH, Asada M, Yoshimatsu K, Wakabayashi T. Semba T, et al. Among authors: funahashi y. Clin Cancer Res. 2004 Feb 15;10(4):1430-8. doi: 10.1158/1078-0432.ccr-0109-03. Clin Cancer Res. 2004. PMID: 14977846

6

E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition.

Matsui J, Yamamoto Y, Funahashi Y, Tsuruoka A, Watanabe T, Wakabayashi T, Uenaka T, Asada M. Matsui J, et al. Among authors: funahashi y. Int J Cancer. 2008 Feb 1;122(3):664-71. doi: 10.1002/ijc.23131. Int J Cancer. 2008. PMID: 17943726

7

[Preclinical biomarker research and patient stratification of molecular target agents: the anti-angiogenic inhibitor Lenvatinib mesylate (E7080)].

Matsui J, Funahashi Y. Matsui J, et al. Among authors: funahashi y. Nihon Yakurigaku Zasshi. 2013 Oct;142(4):162-6. doi: 10.1254/fpj.142.162. Nihon Yakurigaku Zasshi. 2013. PMID: 24107519 Review. Japanese. No abstract available.

8

Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states.

Yoshida T, Ozawa Y, Kimura T, Sato Y, Kuznetsov G, Xu S, Uesugi M, Agoulnik S, Taylor N, Funahashi Y, Matsui J. Yoshida T, et al. Among authors: funahashi y. Br J Cancer. 2014 Mar 18;110(6):1497-505. doi: 10.1038/bjc.2014.80. Epub 2014 Feb 25. Br J Cancer. 2014. PMID: 24569463 Free PMC article.

9

Eribulin mesylate exerts specific gene expression changes in pericytes and shortens pericyte-driven capillary network in vitro.

Agoulnik SI, Kawano S, Taylor N, Oestreicher J, Matsui J, Chow J, Oda Y, Funahashi Y. Agoulnik SI, et al. Among authors: funahashi y. Vasc Cell. 2014 Mar 1;6(1):3. doi: 10.1186/2045-824X-6-3. Vasc Cell. 2014. PMID: 24581301 Free PMC article.

10

Lenvatinib in combination with golvatinib overcomes hepatocyte growth factor pathway-induced resistance to vascular endothelial growth factor receptor inhibitor.

Nakagawa T, Matsushima T, Kawano S, Nakazawa Y, Kato Y, Adachi Y, Abe T, Semba T, Yokoi A, Matsui J, Tsuruoka A, Funahashi Y. Nakagawa T, et al. Among authors: funahashi y. Cancer Sci. 2014 Jun;105(6):723-30. doi: 10.1111/cas.12409. Epub 2014 Apr 28. Cancer Sci. 2014. PMID: 24689876 Free PMC article.

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