Allen H - Search Results

1

Discovery of thieno[2,3-c]pyridines as potent COT inhibitors.

George D, Friedman M, Allen H, Argiriadi M, Barberis C, Bischoff A, Clabbers A, Cusack K, Dixon R, Fix-Stenzel S, Gordon T, Janssen B, Jia Y, Moskey M, Quinn C, Salmeron JA, Wishart N, Woller K, Yu Z. George D, et al. Among authors: allen h. Bioorg Med Chem Lett. 2008 Sep 15;18(18):4952-5. doi: 10.1016/j.bmcl.2008.08.037. Epub 2008 Aug 14. Bioorg Med Chem Lett. 2008. PMID: 18755587

2

Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-kappa B1 p105.

Jia Y, Quinn CM, Bump NJ, Clark KM, Clabbers A, Hardman J, Gagnon A, Kamens J, Tomlinson MJ, Wishart N, Allen H. Jia Y, et al. Among authors: allen h. Arch Biochem Biophys. 2005 Sep 1;441(1):64-74. doi: 10.1016/j.abb.2005.06.020. Arch Biochem Biophys. 2005. PMID: 16087150

3

Comparative analysis of various in vitro COT kinase assay formats and their applications in inhibitor identification and characterization.

Jia Y, Quinn CM, Clabbers A, Talanian R, Xu Y, Wishart N, Allen H. Jia Y, et al. Among authors: allen h. Anal Biochem. 2006 Mar 15;350(2):268-76. doi: 10.1016/j.ab.2005.11.010. Epub 2005 Nov 30. Anal Biochem. 2006. PMID: 16356459

4

Identification of a selective thieno[2,3-c]pyridine inhibitor of COT kinase and TNF-alpha production.

Cusack K, Allen H, Bischoff A, Clabbers A, Dixon R, Fix-Stenzel S, Friedman M, Gaumont Y, George D, Gordon T, Grongsaard P, Janssen B, Jia Y, Moskey M, Quinn C, Salmeron A, Thomas C, Wallace G, Wishart N, Yu Z. Cusack K, et al. Among authors: allen h. Bioorg Med Chem Lett. 2009 Mar 15;19(6):1722-5. doi: 10.1016/j.bmcl.2009.01.088. Epub 2009 Jan 30. Bioorg Med Chem Lett. 2009. PMID: 19217782

5

Structure-based design of caspase-1 inhibitor containing a diphenyl ether sulfonamide.

Shahripour AB, Plummer MS, Lunney EA, Sawyer TK, Stankovic CJ, Connolly MK, Rubin JR, Walker NP, Brady KD, Allen HJ, Talanian RV, Wong WW, Humblet C. Shahripour AB, et al. Among authors: allen hj. Bioorg Med Chem Lett. 2001 Oct 22;11(20):2779-82. doi: 10.1016/s0960-894x(01)00573-x. Bioorg Med Chem Lett. 2001. PMID: 11591522

6

Structure-based design of nonpeptide inhibitors of interleukin-1beta converting enzyme (ICE, caspase-1).

Shahripour AB, Plummer MS, Lunney EA, Albrecht HP, Hays SJ, Kostlan CR, Sawyer TK, Walker NP, Brady KD, Allen HJ, Talanian RV, Wong WW, Humblet C. Shahripour AB, et al. Bioorg Med Chem. 2002 Jan;10(1):31-40. doi: 10.1016/s0968-0896(01)00250-4. Bioorg Med Chem. 2002. PMID: 11738604

7

Succinic acid amides as P2-P3 replacements for inhibitors of interleukin-1beta converting enzyme (ICE or caspase 1).

Galatsis P, Caprathe B, Gilmore J, Thomas A, Linn K, Sheehan S, Harter W, Kostlan C, Lunney E, Stankovic C, Rubin J, Brady K, Allen H, Talanian R. Galatsis P, et al. Among authors: allen h. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5184-90. doi: 10.1016/j.bmcl.2010.07.004. Epub 2010 Jul 8. Bioorg Med Chem Lett. 2010. PMID: 20656488

8

Inhibition of interleukin-1beta converting enzyme (ICE or caspase 1) by aspartyl acyloxyalkyl ketones and aspartyl amidooxyalkyl ketones.

Galatsis P, Caprathe B, Downing D, Gilmore J, Harter W, Hays S, Kostlan C, Linn K, Lunney E, Para K, Thomas A, Warmus J, Allen H, Brady K, Talanian R, Walker N. Galatsis P, et al. Among authors: allen h. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5089-94. doi: 10.1016/j.bmcl.2010.07.031. Epub 2010 Jul 11. Bioorg Med Chem Lett. 2010. PMID: 20674352

9

Identification and characterization of ICH-2, a novel member of the interleukin-1 beta-converting enzyme family of cysteine proteases.

Kamens J, Paskind M, Hugunin M, Talanian RV, Allen H, Banach D, Bump N, Hackett M, Johnston CG, Li P, et al. Kamens J, et al. Among authors: allen h. J Biol Chem. 1995 Jun 23;270(25):15250-6. doi: 10.1074/jbc.270.25.15250. J Biol Chem. 1995. PMID: 7797510 Free article.

10

Effects of unsaturated fatty acids on interleukin-1beta production by human monocytes.

Rothman D, Allen H, Herzog L, Pilapil A, Seiler CM, Zurier RB. Rothman D, et al. Among authors: allen h. Cytokine. 1997 Dec;9(12):1008-12. doi: 10.1006/cyto.1997.0304. Cytokine. 1997. PMID: 9417812

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